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Research Associate – Immunofluorescence

Danvers, MA

Cell Signaling Technology, Inc. (CST) is a worldwide leader in the development and commercialization of antibodies and assays for pathway analysis, as well as novel discovery technologies such as PhosphoScan®. We are committed to developing innovative new research tools to help define the mechanisms underlying cell function and disease, thereby broadly accelerating progress in biomedical research and medicine.

We are currently seeking a highly motivated and detail-oriented individual for a Research Associate position withinin the Cytometry Group. The candidate will contribute to the innovation, development, and support of research tools, with a primary focus on the evaluation of antibodies in fluorescence microscopy.


  • Analyze antibody performance in cell and tissue-based imaging assays. Techniques include both high-throughput, plate-based imaging, as well as low-throughput, high-resolution microscopy.
  • Collaborate with project scientists and survey recent literature to design and execute experiments that demonstrate antibody specificity in relevant cell/tissue models.
  • Cell culture and tissue processing (including frozen and paraffin-embedded samples).
  • Develop and optimize staining protocols for new antibody targets.
  • Independently perform standard qualitative and quantitative data analyses, and communicate results to senior scientists.
  • Identify, analyze and troubleshoot technical issues relating to development and quality control.
  • Must complete scientific and technical tasks on aggressive timelines, adapt to changing priorities and manage a complex and varied target pipeline.


  • BA, BS or MS degree in a biological science (e.g., molecular biology, biochemistry, or biotechnology).
  • 1-2 years of post-graduate laboratory experience preferred.
  • Enthusiastic and motivated collaborator with strong interpersonal skills.
  • Good communication (written and oral) skills and the ability to work in a multidisciplinary team environment are essential.
  • Proficiency with mainstream computer software is required (e.g. Microsoft Office).
  • Previous experience with confocal microscopy, spectral imaging, immunofluorescence, immunohistochemistry, and/or HTS/HCS techniques is strongly preferred.
  • Knowledge of signal transduction, cell culture, and tissue processing techniques is preferred.


You will be taken to an external website, please attach your cover letter and resume as one document and refer to job code RAIF-2014-16-R when applying.