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The development and characterization of mouse models is critical for drug discovery and the advancement of our understanding of basic cancer biology.

A growing number of antibodies from Cell Signaling Technology have been validated by our IHC group for use on mouse tissue. Our IHC-validated rabbit monoclonal antibodies demonstrate the exceptional specificity, sensitivity and performance required for credible results in challenging applications such as IHC, while eliminating problems seen with mouse on mouse staining.

HS1 Mouse Model Data

Immunohistochemical analysis of paraffin-embedded mouse spleen using HS1 (D5A9) XP® Rabbit mAb (Rodent Specific) #3892.

Stat3 Mouse Model Data

Immunohistochemical analysis of paraffin-embedded Apc (min/+) mouse intestine, using Phosho-Stat3 (Tyr705) (D3A7) XP® Rabbit mAb #9145.

Mouse Model Product List

No. Product Name
No. Product Name
9638 14-3-3 τ Antibody
2855 Phospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb
9644 4E-BP1 (53H11) Rabbit mAb
12705 ABCC4 (D2Q2O) Rabbit mAb
3676 Acetyl-CoA Carboxylase (C83B10) Rabbit mAb
3662 Acetyl-CoA Carboxylase Antibody
3661 Phospho-Acetyl-CoA Carboxylase (Ser79) Antibody
4970 β-Actin (13E5) Rabbit mAb
4968 Pan-Actin Antibody
12796 AFAP1L2/XB130 (D4A5) Rabbit mAb
4060 Phospho-Akt (Ser473) (D9E) XP® Rabbit mAb
3787 Phospho-Akt (Ser473) (736E11) Rabbit mAb
2938 Akt1 (C73H10) Rabbit mAb
4691 Akt (pan) (C67E7) Rabbit mAb
4685 Akt (pan) (11E7) Rabbit mAb
4179 α-Synuclein (D37A6) XP® Rabbit mAb
2535 Phospho-AMPKα (Thr172) (40H9) Rabbit mAb
9221 Phospho-ATF-2 (Thr71) Antibody
9226 ATF-2 (20F1) Rabbit mAb
13007 Atg5 (D6M7Q) Rabbit mAb
2439 ATGL (30A4) Rabbit mAb
2138 ATGL Antibody
2764 Bcl-xL (54H6) Rabbit mAb
2933 Bim (C34C5) Rabbit mAb
3177 BiP (C50B12) Rabbit mAb
4068 Pan-Cadherin Antibody
3195 E-Cadherin (24E10) Rabbit mAb
2173 Calbindin (C26D12) Rabbit mAb
9664 Cleaved Caspase-3 (Asp175) (5A1E) Rabbit mAb
9661 Cleaved Caspase-3 (Asp175) Antibody
9662 Caspase-3 Antibody
9582 β-Catenin (6B3) Rabbit mAb
9587 β-Catenin Antibody (Carboxy-terminal Antigen)
9562 β-Catenin Antibody
2309 γ-Catenin Antibody
3267 Caveolin-1 (D46G3) XP® Rabbit mAb
3238 Caveolin-1 Antibody
12439 CD82 (D7G6H) Rabbit mAb
2680 p35/25 (C64B10) Rabbit mAb
2316 CDK9 (C12F7) Rabbit mAb
12306 CDX2 (D11D10) Rabbit mAb
12644 CLIC4 (D2A7D) Rabbit mAb
3502 Cortactin Antibody
9198 Phospho-CREB (Ser133) (87G3) Rabbit mAb
9197 CREB (48H2) Rabbit mAb
12251 Phospho-M-CSF Receptor (Tyr699) (D10B11) Rabbit mAb
3418 CTCF (D31H2) XP® Rabbit mAb
12294 CUEDC2 Antibody
3512 Connexin 43 Antibody
2978 Cyclin D1 (92G2) Rabbit mAb
4280 Cytochrome c (136F3) Rabbit mAb
2306 DARPP-32 (19A3) Rabbit mAb
12680 SignalSilence® γ-Catenin siRNA II (Mouse Specific)
12309 DNMT3L Antibody (Mouse Specific)
2294 DRAK2 (33D7) Rabbit mAb
12258 E2A (D2B1) Rabbit mAb
12469 EDC3 Antibody
4407 Phospho-EGF Receptor (Tyr1173) (53A5) Rabbit mAb
4153 EGR1 (15F7) Rabbit mAb
3411 eIF3A (D51F4) XP® Rabbit mAb
2067 eIF4E (C46H6) Rabbit mAb
9742 eIF4E Antibody
2469 eIF4G (C45A4) Rabbit mAb
2858 eIF4GI Antibody
2498 eIF4G Antibody
4370 Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP® Rabbit mAb
4376 Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (20G11) Rabbit mAb
4695 p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb
9102 p44/42 MAPK (Erk1/2) Antibody
12017 Everolimus
3145 Ezrin Antibody
3149 Phospho-Ezrin (Thr567)/Radixin (Thr564)/Moesin (Thr558) (41A3) Rabbit mAb
3142 Ezrin/Radixin/Moesin Antibody
3180 Fatty Acid Synthase (C20G5) Rabbit mAb
2251 FosB (5G4) Rabbit mAb
2880 FoxO1 (C29H4) Rabbit mAb
12745 Phospho-Gab1 (Tyr659) Antibody
2118 GAPDH (14C10) Rabbit mAb
3535 GATA-1 (D52H6) XP® Rabbit mAb
13411 GATA-3 (D13C9) XP® Rabbit mAb (PE Conjugate)
12794 GLDC Antibody
2760 Glucagon Antibody
3891 Phospho-Glycogen Synthase (Ser641) Antibody
9331 Phospho-GSK-3α/β (Ser21/9) Antibody
9323 Phospho-GSK-3β (Ser9) (5B3) Rabbit mAb
9315 GSK-3β (27C10) Rabbit mAb
12708 HER3/ErbB3 (D22C5) XP® Rabbit mAb
2867 Hexokinase II (C64G5) Rabbit mAb
2024 Hexokinase I (C35C4) Rabbit mAb
2578 Histone H2A Antibody II
9718 Phospho-Histone H2A.X (Ser139) (20E3) Rabbit mAb
2577 Phospho-Histone H2A.X (Ser139) Antibody
2571 Acetyl-Histone H2B (Lys20) Antibody
9714 Phospho-Histone H3 (Thr3) Antibody
9701 Phospho-Histone H3 (Ser10) Antibody
9751 Tri-Methyl-Histone H3 (Lys4) (C42D8) Rabbit mAb
9727 Tri-Methyl-Histone H3 (Lys4) Antibody
9733 Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit mAb
9756 Tri-Methyl-Histone H3 (Lys27) Antibody
9649 Acetyl-Histone H3 (Lys9) (C5B11) Rabbit mAb
9671 Acetyl-Histone H3 (Lys9) Antibody
9675 Acetyl-Histone H3 (Lys18) Antibody
9725 Di-Methyl-Histone H3 (Lys4) (C64G9) Rabbit mAb
9753 Di-Methyl-Histone H3 (Lys9) Antibody
2901 Di-Methyl-Histone H3 (Lys36) (C75H12) Rabbit mAb
12230 Histone H3 (D1H2) XP® Rabbit mAb (Alexa Fluor® 647 Conjugate)
4499 Histone H3 (D1H2) XP® Rabbit mAb
9715 Histone H3 Antibody
2594 Acetyl-Histone H4 (Lys8) Antibody
2623 HP1α/β (C7F11) Rabbit mAb
2616 HP1α Antibody
3892 HS1 (D5A9) XP® Rabbit mAb (Rodent Specific)
4356 HSF1 Antibody
12594 HSP27 Antibody Sampler Kit
4871 HSP40 (C64B4) Rabbit mAb
4872 HSP70 Antibody
4876 HSP70 (D69) Antibody
4877 HSP90 (C45G5) Rabbit mAb
4875 HSP90 (E289) Antibody
4874 HSP90 Antibody
12038 ID3 (D16D10) Rabbit mAb (Alexa Fluor® 647 Conjugate)
3014 Insulin (C27C9) Rabbit mAb
4593 C-Peptide Antibody
4590 Insulin Antibody
13014 IRF-7 (D2A1J) Rabbit mAb
2361 Phospho-c-Jun (Ser63) (54B3) Rabbit mAb
9164 Phospho-c-Jun (Ser73) Antibody
9165 c-Jun (60A8) Rabbit mAb
12173 KLF4 (D1F2) Rabbit mAb
12586 Lamin B1 (D4Q4Z) Rabbit mAb
9166 LAT Antibody
2088 LEDGF (C57G11) Rabbit mAb
2230 LEF1 (C12A5) Rabbit mAb
12647 Lefty1 (D7E3G) Rabbit mAb
3978 LIN28A (A177) Antibody
2184 LSD1 (C69G12) Rabbit mAb
2139 LSD1 Antibody
2796 Lyn (C13F9) Rabbit mAb
3007 Phospho-MAPKAPK-2 (Thr334) (27B7) Rabbit mAb
4631 Phospho-p38 MAPK (Thr180/Tyr182) (12F8) Rabbit mAb
9212 p38 MAPK Antibody
9218 p38α MAPK Antibody
12079 MCM2 (1E7) Mouse mAb
12838 Mouse MCP-1
2338 Phospho-MEK1/2 (Ser221) (166F8) Rabbit mAb
2071 Mili Antibody
2079 Miwi (G82) Antibody
3801 MMP-7 (D4H5) XP® Rabbit mAb
4895 Mre11 Antibody
2017 MSH2 (D24B5) XP® Rabbit mAb
12146 Phospho-NEDD4L (Ser342) (D16D6) Rabbit mAb
2754 NEDD8 (19E3) Rabbit mAb
2745 NEDD8 Antibody
2837 Neurofilament-L (C28E10) Rabbit mAb
2835 Neurofilament-L (DA2) Mouse mAb
2836 Neurofilament-H (RMdO 20) Mouse mAb
2838 Neurofilament-M (RMO 14.9) Mouse mAb
3366 Neuropilin-2 (D39A5) XP® Rabbit mAb
4764 NF-κB p65 (C22B4) Rabbit mAb
4231 nNOS (C7D7) Rabbit mAb
4236 nNOS (C12H1) Rabbit mAb
4234 nNOS Antibody
3541 Phospho-NPM (Thr199) Antibody
3542 NPM Antibody
12938 O-GlcNAc (CTD110.6) Mouse mAb (HRP Conjugate)
12184 p27 Kip1 (D69C12) XP® Rabbit mAb (PE Conjugate)
12571 Phospho-p53 (Ser15) (D4S1H) XP® Rabbit mAb (Mouse Specific)
2708 p70 S6 Kinase (49D7) Rabbit mAb
3505 Asymmetric-Methyl-PABP1 (Arg455/Arg460) (C60A10) Rabbit mAb
12479 PANK2 (D11E2) Rabbit mAb (Mouse Specific)
12412 PAX3 Antibody
2586 PCNA (PC10) Mouse mAb
3174 PDGF Receptor α (D1E1E) XP® Rabbit mAb
3164 PDGF Receptor α Antibody
3169 PDGF Receptor β (28E1) Rabbit mAb
4564 PDGF Receptor β (C82A3) Rabbit mAb
2446 PDI Antibody
3470 Perilipin (D418) Antibody
4249 PI3 Kinase p110α (C73F8) Rabbit mAb
12144 SignalSilence® PKD2 siRNA I
4735 Phospho-Rpb1 CTD (Ser2/5) Antibody
2581 Phospho-PP1α (Thr320) Antibody
2290 PP2A B Subunit (100C1) Rabbit mAb
2259 PP2A C Subunit (52F8) Rabbit mAb
2038 PP2A C Subunit Antibody
2435 PPARγ (C26H12) Rabbit mAb
2997 Phospho-PRAS40 (Thr246) (C77D7) Rabbit mAb
2691 PRAS40 (D23C7) XP® Rabbit mAb
12446 PSMA3 (D4Y9O) Rabbit mAb
13267 PSMB6 (E1K9O) Rabbit mAb
2412 PA28γ Antibody
9188 PTEN (D4.3) XP® Rabbit mAb
9559 PTEN (138G6) Rabbit mAb
9417 Phospho-Tyrosine Mouse mAb (P-Tyr-100) (Biotinylated)
2258 PU.1 (9G7) Rabbit mAb
2266 PU.1 Antibody
3205 Pyruvate Dehydrogenase (C54G1) Rabbit mAb
12290 RCAS1 (D2B6N) XP® Rabbit mAb
12118 SignalSilence® S100P siRNA I
4858 Phospho-S6 Ribosomal Protein (Ser235/236) (D57.2.2E) XP® Rabbit mAb
4857 Phospho-S6 Ribosomal Protein (Ser235/236) (91B2) Rabbit mAb
2211 Phospho-S6 Ribosomal Protein (Ser235/236) Antibody
2217 S6 Ribosomal Protein (5G10) Rabbit mAb
12136 SignalSilence® Sall4 siRNA I
12361 SAMHD1 Antibody
2794 SCD1 (C12H5) Rabbit mAb
12316 Phospho-Scribble (Ser1220) (D8A2) Rabbit mAb
13180 4F2hc/CD98 (D6O3P) Rabbit mAb
12691 xCT/SLC7A11 (D2M7A) Rabbit mAb
13177 Phospho-SLP-76 (Ser376) Antibody
4958 SLP-76 Antibody
12760 SMARCC2/BAF170 (D8O9V) Rabbit mAb
12024 Smurf2 (D8B8) Rabbit mAb
3728 Sox2 (C70B1) Rabbit mAb (IHC Preferred)
12071 SPHK1 (D1H1L) Rabbit mAb
12191 SPT16 (D7I2K) Rabbit mAb
12858 Src (36D10) Rabbit mAb (Alexa Fluor® 647 Conjugate)
2191 SRC-1 (128E7) Rabbit mAb
9145 Phospho-Stat3 (Tyr705) (D3A7) XP® Rabbit mAb
9359 Phospho-Stat5 (Tyr694) (C11C5) Rabbit mAb
4940 SUMO-1 (C9H1) Rabbit mAb
4930 SUMO-1 Antibody
2808 Survivin (71G4B7) Rabbit mAb
2647 α-Synuclein (Syn204) Mouse mAb
2644 α/β-Synuclein (Syn205) Mouse mAb
12259 TAP2 Antibody
4019 Tau (Tau46) Mouse mAb
12578 TBP (D5G7Y) Rabbit mAb
12498 Tris Buffered Saline (TBS-10X)
2203 TCF1 (C63D9) Rabbit mAb
2429 Thioredoxin 1 (C63C6) Rabbit mAb
4124 TIF1β (C42G12) Rabbit mAb
12978 TMEM49/VMP1 (D6N4G) Rabbit mAb
2128 β-Tubulin (9F3) Rabbit mAb
2146 β-Tubulin Antibody
2148 α/β-Tubulin Antibody
2125 α-Tubulin (11H10) Rabbit mAb
2144 α-Tubulin Antibody
4466 β3-Tubulin (TU-20) Mouse mAb
4890 UBE1a Antibody
13142 SignalSilence® UBE2T siRNA I
12577 USP13 (D4P3M) Rabbit mAb
4866 VDAC Antibody
2479 VEGF Receptor 2 (55B11) Rabbit mAb
2705 Zap-70 (99F2) Rabbit mAb