Many IHC-validated antibodies from Cell Signaling Technology (CST) are directed against proteins that play a critical role in human diseases including cancer, diabetes, obesity, and immune disorders. The list below is a select group of antibodies, identified as performing ideally for immunohistochemical studies. The purpose of this list is to support the advancement of translation studies, furthering the understanding of research targets relevant in a clinical setting.

Selected Product Listing for Clinically Relevant Targets

No. Name
No. Name
2855 Phospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb
9644 4E-BP1 (53H11) Rabbit mAb
4970 β-Actin (13E5) Rabbit mAb
3700 β-Actin (8H10D10) Mouse mAb
4060 Phospho-Akt (Ser473) (D9E) XP® Rabbit mAb
2938 Akt1 (C73H10) Rabbit mAb
4691 Akt (pan) (C67E7) Rabbit mAb
3633 ALK (D5F3™) XP® Rabbit mAb
4336 AML1 (D33G6) XP® Rabbit mAb
3796 α-Amylase (D55H10) XP® Rabbit mAb
5153 Androgen Receptor (D6F11) XP® Rabbit mAb
2087 Axin1 (C76H11) Rabbit mAb
8661 Axl (C89E7) Rabbit mAb
2774 Bax Antibody (Human Specific)
2764 Bcl-xL (54H6) Rabbit mAb
2933 Bim (C34C5) Rabbit mAb
8547 Btk (D3H5) Rabbit mAb
8225 CACYBP (D43G11) Rabbit mAb
3195 E-Cadherin (24E10) Rabbit mAb
2173 Calbindin (C26D12) Rabbit mAb
9579 Cleaved Caspase-3 (Asp175) (D3E9) Rabbit mAb
8480 β-Catenin (D10A8) XP® Rabbit mAb
9582 β-Catenin (6B3) Rabbit mAb
9587 β-Catenin Antibody (Carboxy-terminal Antigen)
3267 Caveolin-1 (D46G3) XP® Rabbit mAb
3528 CD31 (PECAM-1) (89C2) Mouse mAb
3569 CD34 (ICO115) Mouse mAb
3570 CD44 (156-3C11) Mouse mAb
3575 CD45 (136-4B5) Mouse mAb
4915 CD54/ICAM-1 Antibody
12306 CDX2 (D11D10) Rabbit mAb
2383 CEA/CD66e (CB30) Mouse mAb
2197 Phospho-Chk2 (Thr68) (C13C1) Rabbit mAb
12282 Cox2 (D5H5) XP® Rabbit mAb
9198 Phospho-CREB (Ser133) (87G3) Rabbit mAb
9197 CREB (48H2) Rabbit mAb
2978 Cyclin D1 (92G2) Rabbit mAb
5583 DDR1 (D1G6) XP® Rabbit mAb
3777 Phospho-EGF Receptor (Tyr1068) (D7A5) XP® Rabbit mAb
4407 Phospho-EGF Receptor (Tyr1173) (53A5) Rabbit mAb
2085 EGF Receptor (E746-A750del Specific) (D6B6) XP® Rabbit mAb
3197 EGF Receptor (L858R Mutant Specific) (43B2) Rabbit mAb
4267 EGF Receptor (D38B1) XP® Rabbit mAb
2067 eIF4E (C46H6) Rabbit mAb
2929 EpCAM (VU1D9) Mouse mAb
4370 Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP® Rabbit mAb
5246 Ezh2 (D2C9) XP® Rabbit mAb
3145 Ezrin Antibody
4233 Fas (C18C12) Rabbit mAb
3180 Fatty Acid Synthase (C20G5) Rabbit mAb
9740 FGF Receptor 1 (D8E4) XP® Rabbit mAb
4574 FGF Receptor 3 (C51F2) Rabbit mAb
2880 FoxO1 (C29H4) Rabbit mAb
5852 GATA-3 (D13C9) XP® Rabbit mAb
3670 GFAP (GA5) Mouse mAb
8233 Glucagon (D16G10) XP® Rabbit mAb
9323 Phospho-GSK-3β (Ser9) (5B3) Rabbit mAb
7558 HDAC6 (D2E5) Rabbit mAb
2243 Phospho-HER2/ErbB2 (Tyr1221/1222) (6B12) Rabbit mAb
4290 HER2/ErbB2 (D8F12) XP® Rabbit mAb
4791 Phospho-HER3/ErbB3 (Tyr1289) (21D3) Rabbit mAb
2842 Phospho-HER3/ErbB3 (Tyr1289) (D1B5) Rabbit mAb
2867 Hexokinase II (C64G5) Rabbit mAb
2024 Hexokinase I (C35C4) Rabbit mAb
9718 Phospho-Histone H2A.X (Ser139) (20E3) Rabbit mAb
9701 Phospho-Histone H3 (Ser10) Antibody
9709 Phospho-HSP27 (Ser82) (D1H2) XP® Rabbit mAb
2402 HSP27 (G31) Mouse mAb
4876 HSP70 (D69) Antibody
4877 HSP90 (C45G5) Rabbit mAb
3027 IGF-I Receptor β Antibody
3014 Insulin (C27C9) Rabbit mAb
4593 C-Peptide Antibody
9699 Integrin β1 (D2E5) Rabbit mAb
3230 Jak2 (D2E12) XP® Rabbit mAb
3753 JunB (C37F9) Rabbit mAb
4545 Pan-Keratin (C11) Mouse mAb
4548 Keratin 18 (DC10) Mouse mAb
4546 Keratin 8/18 (C51) Mouse mAb
9027 Ki-67 (D2H10) Rabbit mAb (IHC Specific)
9449 Ki-67 (8D5) Mouse mAb
3984 Keratin 17/19 (D32D9) XP® Rabbit mAb
4558 Keratin 19 (BA17) Mouse mAb
2984 Lck (D88) XP® Rabbit mAb
3582 LDHA (C4B5) Rabbit mAb
3558 LDHA/LDHC (C28H7) Rabbit mAb
3289 5-Lipoxygenase (C49G1) Rabbit mAb
3007 Phospho-MAPKAPK-2 (Thr334) (27B7) Rabbit mAb
4511 Phospho-p38 MAPK (Thr180/Tyr182) (D3F9) XP® Rabbit mAb
3619 MCM2 (D7G11) XP® Rabbit mAb
4012 MCM3 Antibody
3735 MCM7 (D10A11) XP® Rabbit mAb
2338 Phospho-MEK1/2 (Ser221) (166F8) Rabbit mAb
3077 Phospho-Met (Tyr1234/1235) (D26) XP® Rabbit mAb
8198 Met (D1C2) XP® Rabbit mAb
3852 MMP-9 Antibody
2017 MSH2 (D24B5) XP® Rabbit mAb
2976 Phospho-mTOR (Ser2448) (49F9) Rabbit mAb (IHC Specific)
4538 MUC1 (VU4H5) Mouse mAb
4903 Nanog (D73G4) XP® Rabbit mAb
3576 CD56 (NCAM) (123C3) Mouse mAb
2837 Neurofilament-L (C28E10) Rabbit mAb
8242 NF-κB p65 (D14E12) XP® Rabbit mAb
6956 NF-κB p65 (L8F6) Mouse mAb
3608 Notch1 (D1E11) XP® Rabbit mAb
3542 NPM Antibody
3625 NUT (C52B1) Rabbit mAb
2890 Oct-4A (C52G3) Rabbit mAb
2947 p21 Waf1/Cip1 (12D1) Rabbit mAb
2527 p53 (7F5) Rabbit mAb
5625 Cleaved PARP (Asp214) (D64E10) XP® Rabbit mAb
2586 PCNA (PC10) Mouse mAb
9535 PDCD4 (D29C6) XP® Rabbit mAb
5241 PDGF Receptor α (D13C6) XP® Rabbit mAb
4564 PDGF Receptor β (C82A3) Rabbit mAb
4249 PI3 Kinase p110α (C73F8) Rabbit mAb
4053 PKM2 (D78A4) XP® Rabbit mAb
2435 PPARγ (C26H12) Rabbit mAb
2997 Phospho-PRAS40 (Thr246) (C77D7) Rabbit mAb
2691 PRAS40 (D23C7) XP® Rabbit mAb
8757 Progesterone Receptor A/B (D8Q2J) XP® Rabbit mAb
3157 Progesterone Receptor B (C1A2) Rabbit mAb
2475 PSA/KLK3 (D11E1) XP® Rabbit mAb
3409 PSD95 (D74D3) XP® Rabbit mAb
9188 PTEN (D4.3) XP® Rabbit mAb
3205 Pyruvate Dehydrogenase (C54G1) Rabbit mAb
8965 RARγ1 (D3A4) XP® Rabbit mAb
9309 Rb (4H1) Mouse mAb
3287 ROS1 (D4D6™) Rabbit mAb
8637 RRM1 (D12F12) XP® Rabbit mAb
4858 Phospho-S6 Ribosomal Protein (Ser235/236) (D57.2.2E) XP® Rabbit mAb
5364 Phospho-S6 Ribosomal Protein (Ser240/244) (D68F8) XP® Rabbit mAb
2217 S6 Ribosomal Protein (5G10) Rabbit mAb
2317 S6 Ribosomal Protein (54D2) Mouse mAb
4668 Phospho-SAPK/JNK (Thr183/Tyr185) (81E11) Rabbit mAb
2093 SCF (C19H6) Rabbit mAb
2652 Skp2 (D3G5) XP® Rabbit mAb
9585 Slug (C19G7) Rabbit mAb
3579 Sox2 (D6D9) XP® Rabbit mAb
8725 SPARC (D10F10) Rabbit mAb
2109 Src (36D10) Rabbit mAb
2191 SRC-1 (128E7) Rabbit mAb
9167 Phospho-Stat1 (Tyr701) (58D6) Rabbit mAb
9145 Phospho-Stat3 (Tyr705) (D3A7) XP® Rabbit mAb
4113 Phospho-Stat3 (Tyr705) (M9C6) Mouse mAb
9359 Phospho-Stat5 (Tyr694) (C11C5) Rabbit mAb
4191 Phospho-Stathmin (Ser38) (D19H10) Rabbit mAb
3352 Stathmin Antibody
2808 Survivin (71G4B7) Rabbit mAb
2647 α-Synuclein (Syn204) Mouse mAb
4019 Tau (Tau46) Mouse mAb
3557 TGM2 (D11A6) XP® Rabbit mAb
9045 Thymidylate Synthase (D5B3) XP® Rabbit mAb
3219 TRAIL (C92B9) Rabbit mAb
2508 TrkA (14G6) Rabbit mAb
4607 TrkB (80G2) Rabbit mAb
5666 β3-Tubulin (D65A4) XP® Rabbit mAb
9319 Tyrosinase (T311) Mouse mAb (IHC Specific)
3933 Ubiquitin Antibody
2479 VEGF Receptor 2 (55B11) Rabbit mAb
9698 VEGF Receptor 2 (D5B1) Rabbit mAb
5741 Vimentin (D21H3) XP® Rabbit mAb
8418 YAP/TAZ (D24E4) Rabbit mAb
8475 YB1 (D2B12) Rabbit mAb
2705 Zap-70 (99F2) Rabbit mAb