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Keratin 7 Antibody #3473
This product is discontinued
Gallery: Keratin 7 Antibody #3473
Keratin 7 Antibody detects endogenous levels of keratin 7 protein.Species predicted to react based on 100% sequence homology: Monkey
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to amino acids at the amino-terminus of human keratin 7. Polyclonal antibodies are purified by Protein A and peptide affinity chromatography.
Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as research biomarkers (1). Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6).
Keratin 7 and Keratin 19 are present in hepatic and pancreatic progenitor/stem cells (7,8).
For Research Use Only. Not For Use In Diagnostic Procedures. Cell Signaling Technology® is a trademark of Cell Signaling Technology, Inc.