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Product Usage Information

Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

Specificity / Sensitivity

FABP1 Antibody recognizes endogenous levels of total FABP1 protein.

Source / Purification

Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val101 of human FABP1 protein. Antibodies are purified by protein A and peptide affinity chromatography.

Fatty acid binding proteins (FABPs) bind to fatty acids and other lipids to function as cytoplasmic lipid chaperones (1,2). They participate in the transport of fatty acids and other lipids to various cellular pathways (2). Research studies have shown that common variants of the human liver fatty acid binding protein gene FABP1 play a role in the development of type 2 diabetes and insulin resistance (3).

1.  Tuncman, G. et al. (2006) Proc Natl Acad Sci U S A 103, 6970-5.

2.  Haunerland, N.H. and Spener, F. (2004) Prog Lipid Res 43, 328-49.

3.  Mansego, M.L. et al. (2012) PLoS One 7, e31853.

Entrez-Gene Id 2168
Swiss-Prot Acc. P07148

For Research Use Only. Not For Use In Diagnostic Procedures.
Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.

FABP1 Antibody