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AMPKAMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3). The kinase is activated by an elevated AMP/ATP ratio due to cellular and environmental stress, such as heat shock, hypoxia, and ischemia. Listed below are CST products for AMPK research including:
- Total Protein and Phospho-site Specific Antibodies.
- Antibody Sampler Kits, PathScan® ELISA Kits and Antibody Pairs.
- Control Cell Extracts and Blocking Peptides.
- SignalSilence® siRNA.