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Exactly what is ELISA? Learn about the enzyme-linked immunosorbent assay, the specific interaction between antibody & antigen. Click here.
The accuracy of western blot results relies heavily on the quality of the primary antibody used. CST™ antibodies are validated using multiple experiments.
Illustration of Motif Antibody Coverage
This post summarizes the findings in the Nature paper YAP-dependent reprogramming of Lgr5+ stem cells drives intestinal regeneration and cancer.
An outline and examples of the steps performed at Cell Signaling Technology to validate target specificity of an antibody for use in immunohistochemical analysis.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
Catalog numbers in tabular format for control cell extracts and proteins with links to product pages.
Get the reagents and supplies for immunohistochemistry (IHC) protocols including antibodies, diluent, blocking buffer, chromogens, and controls
Learn how to visualize protein expression in tissue with immunohistochemistry (IHC). See examples of successfully optimized IHC assays.
Eliminate non-specific binding and high background with the immunohistochemitry (IHC) troubleshooting guide and positive/negative controls
Case Study 1: Exceptional Specificity of XP Monoclonal Antibodies pertaining to eXceptional Monoclonal Technology (XMT) from Cell Signaling Technology.
Immunohistochemistry is a method for studying antigen localization in tissue sections using antibodies. Learn sample preparation, labeling, & visualization.
Expert-reviewed interactive pathway providing a current overview of ErbB/HER Signaling.
Case Study 4: Exceptional Performance of XP Monoclonal Antibodies from Cell Signaling Technology.
Scientific posters presented by CST scientists at various conferences and trade shows through the years.
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
When EGFR was first reported, the phosphorylation sites and corresponding amino acid numbering did not account for a cleaved signal peptide measuring 24 amino acids in length. Considering many EGFR phospho-sites were reported prior to the discovery of the signal peptide, the amino acid position numbering first reported is slightly shifted from the actual position. These phospho-sites are still referred to by their initially reported amino acid position to maintain consistency in the field and thus our product names maintain this nomenclature as well.
This video introduces PTMScan technology, a platform for the enrichment of post-translational modifications (PTMs) in mass spectrometry-based proteomics studies.
A video tutorial illustrating the methodology behind PTMScan Technology and an example of its use in a recent phosphoproteomic study authored by scientists from CST.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Antibodies that recognize peptide motifs in the phosphorylated state are valuable research tools in western blotting. Learn how to use them in this post.
Mass spectrometry-based proteomic methods like PTMScan can be applied in translational research. For example to identify novel biomarkers of disease
Listing of IHC-related scientific posters and papers involving scientists from Cell Signaling Technology.
Breakthroughs in therapeutic targeting of YAP/TAZ-TEAD signaling using small molecules were presented at AACR 2023. Read a recap of the presentations.
Identification of ALK and ROS1 fusion proteins in non-small cell lung cancer (NSCLC) at Cell Signaling Technology.
List of publications based on primary research done by the Cancer Research Group at CST (2002-2013).
Technical support questions and issues for flow cytometry-validated antibodies and products from CST Cell Signaling Technology
Technical support questions and issues for help with immunofluorescence-validated antibodies and products from CST Cell Signaling Technology
