Caspases, a family of cysteine proteases, are the central regulators of apoptosis. Initiator caspases (i.e., caspase-2, -8, -9, -10, -11, and -12) cleave and activate downstream effector caspases (i.e., caspase-3, -6, and -7), which in turn execute apoptosis by cleaving targeted cellular proteins. Listed below are CST products for caspase research including:
- Antibodies for both Total and Cleaved protein.
- Control Biotinylated and Blocking Peptides, and Activity Assay Kits.
- Antibody Sampler Kits and PathScan® ELISA Kits and Antibody Pairs.
- SignalSilence® siRNA.