Product Pathways - Translational Control
Miwi (D478) Antibody #2025
|2025S||100 µl (10 western blots)||---||In Stock||---|
|2025||carrier free and custom formulation / quantity||email request|
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Species cross-reactivity is determined by western blot.
Applications Key: W=Western Blotting
Specificity / Sensitivity
Miwi (D478) Antibody detects endogenous levels of total Miwi protein.
Source / Purification
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp478 of mouse Miwi. Antibodies are purified by protein A and peptide affinity chromatography.
The Drosophila piwi gene was identified as being required for the self-renewal of germline stem cells (1). Piwi homologs are well conserved among various species including Arabidopsis, C. elegans, and Homo sapiens (1). Both Miwi and Mili proteins are mouse homologs of Piwi and contain a C-terminal Piwi domain (2). Miwi and Mili bind to Piwi-interacting RNAs (piRNAs) in male germ cells and are essential for spermatogenesis in mice (3-5).
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For Research Use Only. Not For Use In Diagnostic Procedures.
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