Product Pathways - Metabolism
Glucagon Antibody #2760
|2760S||100 µl (100 sections)||---||In Stock||---|
|2760||carrier free and custom formulation / quantity||email request|
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|IHC-P||1:100||Human, Mouse, Rat||Endogenous||4||Rabbit|
Applications Key: IHC-P=Immunohistochemistry (Paraffin), IHC-F=Immunohistochemistry (Frozen), IF-F=Immunofluorescence (Frozen)
Specificity / Sensitivity
Glucagon Antibody detects endogenous levels of total glucagon protein.
Source / Purification
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human glucagon. Antibodies are purified by protein A and peptide affinity chromatography.
Immunohistochemical analysis of paraffin-embedded human pancreas, showing staining of α cells, using Glucagon Antibody.
Immunohistochemical analysis of paraffin-embedded mouse pancreas, showing staining of α cells, using Glucagon Antibody.
Glucose homeostasis is regulated by a variety of hormones including glucagon. Glucagon is synthesized as the precursor molecule proglucagon and is proteolytically processed to yield the mature peptide in α cells of the pancreatic islets. Glucagon causes the release of glucose from glycogen and stimulates gluconeogenesis in the liver (1,2).
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For Research Use Only. Not For Use In Diagnostic Procedures.
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