Product Pathways - Metabolism
FABP1 Antibody #5352
|W||H M R||Endogenous||14||Rabbit|
Reactivity Key: H=Human M=Mouse R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
Specificity / Sensitivity
FABP1 Antibody recognizes endogenous levels of total FABP1 protein.
Source / Purification
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val101 of human FABP1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Fatty acid binding proteins (FABPs) bind to fatty acids and other lipids to function as cytoplasmic lipid chaperones (1,2). They participate in the transport of fatty acids and other lipids to various cellular pathways (2). Research studies have shown that common variants of the liver fatty acid binding protein gene, FABP1, play a role in the development of type 2 diabetes and insulin resistance (3).
- Tuncman, G. et al. (2006) Proc Natl Acad Sci U S A 103, 6970-5.
- Haunerland, N.H. and Spener, F. (2004) Prog Lipid Res 43, 328-49.
- Mansego, M.L. et al. (2012) PLoS One 7, e31853.
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For Research Use Only. Not For Use In Diagnostic Procedures.