Signaling Pathways and Tables
These diagrams have been assembled by Cell Signaling Technology (CST) scientists and outside experts to provide succinct and current overviews of selected signal transduction pathways. Knowledge about each signaling pathway has been synthesized and integrated into understandable paradigms of cellular communication. Please send suggestions for developing new pathways to info@cellsignal.com.
The proteins in each pathway are linked to a search on the PhosphoSitePlus® website, which is an expert-curated knowledge base of protein phosphorylation plus other post-translational modifications in vertebrates. A matching collection of product search pathways is also online.
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Chromatin / Epigenetic Regulation
- Protein Acetylation
- Histone Methylation
- Examples of Crosstalk Between Post-Translational Modifications
- Histone Modification Table
MAP Kinase Signaling
- Mitogen-Activated Protein Kinase Cascades
- MAPK/Erk in Growth and Differentiation
- G-Protein-Coupled Receptors Signaling to MAPK/Erk
- SAPK/JNK Signaling Cascades
- Signaling Pathways Activating p38 MAPK
Apoptosis and Autophagy
- Apoptosis Overview
- Inhibition of Apoptosis
- Death Receptor Signaling
- Mitochondrial Control of Apoptosis
- Autophagy Signaling
PI3 Kinase / Akt Signaling
Cellular Metabolism
Translational Control
Cell Cycle / DNA Damage
Immunology and Inflammation
- Jak/Stat Signaling: IL-6 Receptor Family
- Jak/STAT Utilization Table
- Jak and Cytokine Receptor Mutants in
Cancer Table - NF-κB Signaling
- TLR Pathway
- B Cell Receptor Signaling
- T Cell Receptor Signaling
Neuroscience
- Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease
- Dopamine Signaling in Parkinson's Disease
Stem Cells, Development, and Differentiation
- Wnt/β-Catenin Signaling
- Notch Signaling
- Hedgehog Signaling In Vertebrates
- TGF-β Signaling
- Hippo Signaling
- ESC Pluripotency and Differentiation
Cytoskeletal Regulation and Adhesion
Other
