Product Pathways - Motif Antibodies
PTMScan® Phospho-Thr-Pro-Glu Motif (T*PE) Immunoaffinity Beads
|Consenus Site||Cell or Tissue Type||Study No.||Modified Peptides Identified|
|T*PE, T*P||HeLa (human epithelial carcinoma)||2544||465 PDF XLS|
This product is not for individual sale. It is only available as a component of the PTMScan® Proteomics System. PTMScan® Proteomics System orders must be priced out individually. Please email us at email@example.com to receive the most accurate pricing.
PTMScan® Immunoaffinity Beads are custom preparations of motif antibodies coupled to protein A beads. They are intended only for use for PTMScan® and are available as components of the PTMScan® Proteomics System.
Specificity / Sensitivity
PTMScan® Phospho-Thr-Pro-Glu Motif (T*PE) Immunoaffinity Beads detect and capture endogenous levels of peptide derived from protease digested cellular proteins containing phospho-threonine followed by Pro and Glu residues. The antibody also recognize peptides and proteins containing partial motif pTP. (U.S. Patent No's: 6,441,140; 6,982,318; 7,259,022; 7,344,714; U.S.S.N. 11,484,485; and all foreign equivalents.)
Phospho-Thr-Pro-Glu motif is a subgroup of the Phospho-Thr-Pro motif. Phospho-Thr-Prol motif is phosphorylated by proline-directed protein kinases, such as MAP kinases and cyclin dependent kinases (CDKs) belong to this family of kinases. Proline-directed phosphorylation is one of the major regulatory phosphorylation events in many cellular processes such as cell proliferation and differentiation (1-6). CST phospho-Thr-Pro-Glu antibody provides a great tool to study a subset of substrates of proline-directed kinases.
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For Research Use Only. Not For Use In Diagnostic Procedures.