Antibodies for PTMScan^® Discovery

• KinomeView and Serine/Threonine PhosphoScan
• Tyrosine PhosphoScan
• UbiScan
• AcetylScan

Cell Signaling Technology developed Motif Antibodies to enable focused analysis of regulatory post-translational modifications (PTMs). We use these in the form of custom PTMScan License/IAP Bead Products in our PTMScan Discovery Services, and we provide these products with a Per-Use License to enable our customers to perform PTMScan proteomics in-house.

Whether your research objective is to understand specific serine/threonine kinase families or kinome branches, global tyrosine phosphorylation, protein acetylation, or ubiquitin-mediated signaling, our PTMScan Discovery Services and PTMScan License/IAP Beads products provide powerful tools for in-depth proteomic analysis of regulatory PTMs.

PTMScan – PhosphoScan^®, UbiScan^®, AcetylScan^® – is the most effective strategy for PTM proteomics, and our 18 PTMScan License/IAP Bead products (see below) are custom, optimized reagents for immunoaffinity purification (IAP) of serine/threonine and tyrosine phosphopeptides, acetylated peptides and ubiquitin-tagged peptides. PTMScan is a method that combines Motif Antibody-based IAP and tandem mass spectrometry to generate focused and quantitative results about proteins on which PTMs perform key regulatory functions. It is the PTM-specificity of our Motif Antibodies that makes PTMScan Discovery Services and Per-Use Licensing of PTMScan License/IAP Bead products the standards for proteomic analysis of regulatory signaling.