KinomeView® to Serine/Threonine PhosphoScan® Proteomics
Cell Signaling Technology’s KinomeView® and PhosphoScan® proteomics services are a two-step process enabling kinome-wide quantitative analysis of cellular phosphorylation for the discovery and validation of signaling targets, kinase substrates and response biomarkers. PhosphoScan services provide in-depth yet focused phosphoproteome analysis with CST’s patented Phospho-Motif Antibodies. Each of these antibodies react broadly with diverse sets of serine, threonine and tyrosine phosphorylated sequences. Our KinomeView Service provides a first step to guide the design of PhosphoScan studies by determining which branches of the kinome are responsive to the biology or chemistry under investigation. KinomeView can identify which Phospho-Motif Antibodies will yield the greatest insights when used in PhosphoScan mass spectrometry analysis.