Tyrosine PhosphoScan® Proteomics
Tyrosine PhosphoScan® Services provide the most comprehensive strategy for global phospho-tyrosine profiling. CST’s P-Tyr-100 mAb is more broadly reactive with p-Tyr peptides than any other antibody. Employing P-Tyr-100 for phosphopeptide enrichment in combination with LC-MS/MS analysis yields quantitative profiles of hundreds to over a thousand non-redundant phosphorylated sequences.
Tyrosine PhosphoScan proteomics is used routinely and successful for target discovery, mutant RTK screening, lead compound characterization and biomarker discovery.
Tyrosine Workflow Diagram 0.7 MB
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Example Studies and Deliverables
| Description | Antibody | Kit | Consenus Site | LCMS Data & Output Results |
|---|---|---|---|---|
| Phospho-Tyrosine (P-Tyr-100) | 9411 | 5636 | Y* | Mouse Brain XLS RAW |
| Phospho-Tyrosine (P-Tyr-1000) | 8954 | Y* | Mouse Brain XLS RAW |
