Tyrosine PhosphoScan® Proteomics
Tyrosine PhosphoScan® Services provide the most comprehensive strategy for global phospho-tyrosine profiling. CST’s P-Tyr-100 mAb is more broadly reactive with p-Tyr peptides than any other antibody. Employing P-Tyr-100 for phosphopeptide enrichment in combination with LC-MS/MS analysis yields quantitative profiles of hundreds to over a thousand non-redundant phosphorylated sequences.
Tyrosine PhosphoScan proteomics is used routinely and successful for target discovery, mutant RTK screening, lead compound characterization and biomarker discovery.
Tyrosine Workflow Diagram 0.7 MB
Example Studies and Deliverables
|Description||Antibody||Kit||Consenus Site||LCMS Data & Output Results|
|Phospho-Tyrosine (P-Tyr-100)||9411||5636||Y*||Mouse Brain XLS RAW|
|Phospho-Tyrosine (P-Tyr-1000)||8954||8803||Y*||Mouse Brain XLS RAW|