Motif Antibodies
Introduction
Motif specific antibodies are proprietary to CST (Patent, U.S. No. 6,441,140 and Patents Pending) and are engineered to recognize proteins that contain a phosphorylated residue in the context of a specific kinase substrate, binding motif, or other phosphorylation motifs. These reagents are ideal for generic and peptide-based kinase assays. Many are available without carrier protein or glycerol.
| Antibody Name | Product # | Motif Recognized | Peptide |
|---|---|---|---|
| Phospho-Tyrosine Mouse mAb (P-Tyr-100) | 9411 | Y* | p-Tyr |
| Phospho-(Tyr) p85 PI3K Binding Motif Antibody | 3821 | Y*-X-X-M | PDGFR-b (Tyr934) |
| Phospho-(Ser) 14-3-3 Binding Motif (4E2) Mouse mAb | 9606 | R/K-X-X-S*-X-P | cdc25 (Ser216) |
| Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb | 9614 | R-X-R-X-X-S*/T* | BRCA1 (Thr509) |
| Phospho-PKA Substrate (RRXS*/T*) (100G7) Rabbit mAb | 9624 | R-R-X-S*/T* | NMDAR (Ser897) |