SignalSilence® siRNA
Human Targets
| Target | I | II |
|---|---|---|
| 4E-BP1 | 6414 | |
| ABIN-1 | 6603 | 6609 |
| ADAM9 | 11968 | 12085 |
| ADRM1 | 7981 | 8536 |
| Aldolase A | 8966 | |
| Akt | 6211 | 6510 |
| Akt2 | 6396 | |
| AMPKα2 | 6620 | 6630 |
| Apaf-1 | 6229 | |
| APC2 | 11866 | |
| APC3 | 11821 | |
| APC6 | 7279 | 7164 |
| ATF-2 | 6433 | 6443 |
| Atg4A | 6427 | |
| Atg4B | 6336 | |
| Atg4C | 6325 | |
| Atg5 | 6345 | |
| Atg7 | 6604 | |
| Atg9A | 7051 | |
| Atg13 | 12043 | |
| Atg14 | 6286 | 6287 |
| ATM | 6328 | 6329 |
| ATR | 6288 | 6289 |
| Aurora A/AIK | 8883 | |
| Aurora B/AIM1 | 8958 | |
| Axl | 6263 | 6264 |
| β-Arrestin 1 | 6218 | |
| B-Raf | 8935 | 9439 |
| Bad | 6471 | 6512 |
| Bak | 6486 | |
| Bax | 6321 | 6514 |
| Beclin-1 | 6222 | 6246 |
| Bcl-2 | 6441 | 6516 |
| Bcl-xL | 6362 | 6363 |
| Bim | 6461 | 6518 |
| Bmi1 | 6442 | |
| BRCA1 | 12519 | 12642 |
| Bub1b | 6623 | 12150 |
| c-Jun | 6203 | 6204 |
| c-Myc | 6341 | 6552 |
| c-Raf | 12256 | 12342 |
| CA2 | 7670 | 7589 |
| CAND1 | 9824 | |
| Caspase-3 | 6466 | 6520 |
| Caspase-10 | 6357 | |
| β-Catenin | 6225 | 6238 |
| γ-Catenin | 6226 | 6239 |
| Cbl-b | 12130 | 12122 |
| CDC2 | 3500 | 3600 |
| CDK2 | 8618 | 7417 |
| CDK5 | 6216 | 6217 |
| CDK8 | 6438 | |
| CHD1 | 7168 | 7200 |
| Chk1 | 6241 | 6522 |
| Chk2 | 6276 | |
| CK2α | 6389 | |
| Acetyl-CoA Carboxylase 1 | 6224 | 6237 |
| Cofilin | 6267 | 6268 |
| Control | 6568 | |
| Control (Fluorescein Conjugate) | 6201 | |
| CREB | 6588 | 6590 |
| CTCF | 6265 | |
| DDX5 | 8626 | 8627 |
| Dicer | 6576 | 6585 |
| Dopamine β-Hydroxylase | 7664 | |
| EGFR | 6480 | 6482 |
| eIF4E | 6311 | 6554 |
| Eps15 | 12253 | |
| ERCC1 | 8896 | |
| ERK5 | 7301 | |
| EWS | 12175 | 12216 |
| Ezh2 | 6509 | |
| Ezrin | 6475 | |
| FAK | 6472 | 6483 |
| Fatty Acid Synthase | 12588 | 12613 |
| FGF Receptor 2 | 12600 | |
| FGF Receptor 4 | 12472 | 12669 |
| FLIP | 12372 | 12407 |
| FoxO1 | 6242 | 6256 |
| FoxO3a | 6302 | 6303 |
| Fyn | 12473 | |
| FZD6 | 6596 | 6597 |
| Gelsolin | 6469 | 6473 |
| Glucocorticoid Receptor | 6508 | 7699 |
| GSK-3α | 6312 | 6524 |
| GSK-3α/β | 6301 | |
| HDAC4 | 7595 | 7609 |
| HELLS | 11822 | 11823 |
| HER2/ErbB2 | 6282 | 6283 |
| HER3/ErbB3 | 6504 | 6422 |
| hnRNP A0 | 6503 | |
| hnRNP A1 | 7668 | |
| hnRNP E1 | 7798 | 7987 |
| hnRNP LL | 8651 | 8624 |
| HSP27 | 6356 | 6526 |
| HtrA2/Omi | 7574 | |
| IGF-I Receptor | 6610 | |
| ILK1 | 6202 | 6528 |
| IκBα | 6327 | |
| IKKα | 6372 | 6373 |
| IKKβ | 6377 | 6378 |
| IRAK1 | 6253 | 6228 |
| IRF-3 | 6274 |
| Target | I | II |
|---|---|---|
| ISG15 | 12557 | 12621 |
| Jak2 | 6235 | |
| JMJD2B | 7435 | 7062 |
| KEAP1 | 5285 | 5289 |
| KLHL12 | 9410 | 9420 |
| LC3A | 6214 | 6215 |
| LC3B | 6212 | 6213 |
| LIMK1 | 4559 | 7156 |
| LRP6 | 8650 | 8623 |
| MAML1 | 12386 | 12440 |
| MARK2 | 6266 | |
| Mcl-1 | 6315 | |
| MDR1/ABCB1 | 11879 | 11906 |
| MEK1 | 6426 | 6530 |
| MEK2 | 6431 | 6532 |
| Merlin | 6316 | 6338 |
| Met | 6618 | 6622 |
| MetAP2 | 12149 | |
| β2-microglobulin | 7759 | 7774 |
| Miz-1 | 12335 | 12405 |
| MKK3 | 6294 | 6295 |
| MKK7 | 6322 | 6323 |
| Moesin | 6499 | |
| MTAP | 6284 | 6285 |
| mTOR | 6381 | 6556 |
| NDP52 | 8964 | 9000 |
| NDRG1 | 6245 | 6257 |
| NF-κB | 6261 | 6534 |
| NRBF-2 | 6448 | |
| p16 INK4A | 6598 | |
| p21 Waf1/Cip1 | 6456 | 6558 |
| p27 Kip1 | 12324 | 12410 |
| p38 MAPK | 6564 | 6243 |
| p38α MAPK | 6269 | 6277 |
| p38β MAPK | 6278 | 6279 |
| p38γ MAPK | 6632 | 6633 |
| p38δ MAPK | 6600 | 6601 |
| p42 MAPK (Erk2) | 6540 | 6578 |
| p44 MAPK (Erk1) | 6436 | |
| p44/42 MAPK (Erk1/2) | 6560 | |
| p53 | 6231 | 6562 |
| p70/85 | 6566 | 6572 |
| PAK1 | 6361 | 6536 |
| PAK2 | 6467 | 6507 |
| PARP | 6304 | 6305 |
| PDK1 | 6314 | |
| PEA-15 | 7830 | 7865 |
| PERK | 9024 | 9026 |
| PI3K p110α | 6359 | |
| PIAS3 | 9073 | 9031 |
| PKA C-α | 6406 | 6574 |
| PKCε | 7683 | 12318 |
| PKCζ | 8672 | 8939 |
| PKD2 | 12144 | |
| PLCγ1 | 6293 | 6254 |
| PLK1 | 6292 | 12132 |
| PTEN | 6251 | 6538 |
| Puma | 12845 | 12890 |
| Rabex-5 | 6437 | |
| Radixin | 6491 | |
| Rb | 6451 | 6542 |
| RCAS1 | 6463 | 6496 |
| Rictor | 8649 | 8622 |
| RKIP | 6296 | 6297 |
| RMP | 6464 | 6495 |
| RXRα | 6348 | |
| RSK1 | 6313 | 6309 |
| S100P | 12118 | 12114 |
| Sall4 | 12136 | 12111 |
| SAPK/JNK | 6232 | 6233 |
| Sec24B | 12229 | 12333 |
| SHP-2 | 7917 | 7927 |
| SirT1 | 12241 | |
| SirT6 | 9390 | |
| Skp1 | 12514 | |
| Skp2 | 7753 | 7756 |
| Smad1 | 6223 | 6227 |
| SMARCC2 | 7431 | 7624 |
| SP1 | 12104 | 12106 |
| SQSTM1/p62 | 6394 | 6399 |
| Stat1 | 6331 | 6544 |
| Stat3 | 6580 | 6582 |
| Stat5 | 6275 | 6298 |
| Stat6 | 6358 | 9404 |
| Survivin | 6351 | 6546 |
| TAK1 | 6317 | 6318 |
| TLR3 | 6236 | |
| TrkA | 6613 | |
| TTK | 6367 | 6368 |
| Tuberin/TSC2 | 6476 | 6548 |
| UBA2 | 7646 | 7642 |
| UBE2S | 7220 | 7732 |
| UCHL1 | 12353 | 12415 |
| UCHL3 | 7511 | 7339 |
| ULK1 | 7000 | |
| USP9X | 6308 | |
| USP1 | 6490 | 6498 |
| USP10 | 7747 | |
| USP14 | 7158 | |
| VASP | 7637 | 7658 |
| WFS1 | 7044 | |
| XIAP | 6446 | 6550 |
| YB1 | 6206 | 6207 |
