siRNA
Search for SignalSilence® siRNA Products
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Introduction
SignalSilence® siRNA kits and reagents from Cell Signaling Technology (CST) allow the researcher to specifically inhibit protein expression. These products utilize RNA interference, a method in which gene expression can be selectively silenced through the delivery of double stranded RNA molecules into the cell. Two siRNAs are now available for each target (siRNA I and II). A fluorescein-labeled non-targeted siRNA control allows the user to monitor transfection efficiency. In addition, an unconjugated control siRNA can be used to control for specificity. CST’s siRNA kits contain both available siRNAs as well as target antibodies.
Product Data
siRNA Products
| Target | I | II | Kit |
|---|---|---|---|
| Akt | 6211 | 6510 | 6511 |
| Akt2 | 6396 | – | – |
| Bad | 6471 | 6512 | 6513 |
| Bax | 6321 | 6514 | 6515 |
| Bcl-2 | 6441 | 6516 | 6517 |
| Bim | 6461 | 6518 | 6519 |
| c-Myc | 6341 | 6552 | 6553 |
| Caspase-3 | 6466 | 6520 | 6521 |
| Chk1 | 6241 | 6522 | 6523 |
| Control | 6568 | – | – |
| Control (Fluorescein Conjugate) | 6201 | – | – |
| Dicer1 | 6576 | 6585 | 6586 |
| eIF4E | 6311 | 6554 | 6555 |
| GSK-3α | 6312 | 6524 | 6525 |
| GSK-3α/β | 6301 | – | – |
| HSP27 | 6356 | 6526 | 6527 |
| ILK1 | 6202 | 6528 | 6529 |
| JNK1 | – | – | 6583 |
| MEK1 | 6426 | 6530 | 6531 |
| Target | I | II | Kit |
|---|---|---|---|
| MEK2 | 6431 | 6532 | 6533 |
| mTOR | 6381 | 6556 | 6557 |
| NF-κB | 6261 | 6534 | 6535 |
| p21 Waf1/Cip1 | 6456 | 6558 | 6559 |
| p38 MAPK | 6564 | 6243 | 6565 |
| p42 MAPK (Erk2) | 6391 | 6540 | 6541 |
| p44 MAPK (Erk1) | 6436 | – | – |
| p44/42 MAPK (Erk1/2) | 6560 | – | – |
| p53 | 6231 | 6562 | 6563 |
| p70/85 | 6566 | 6572 | 6567 |
| PAK1 | 6361 | 6536 | 6537 |
| PKA C-α | 6406 | 6574 | 6575 |
| PTEN | 6251 | 6538 | 6539 |
| Rb | 6451 | 6542 | 6543 |
| Stat1 | 6331 | 6544 | 6545 |
| Stat3 | 6580 | 6582 | 6583 |
| Survivin | 6351 | 6546 | 6547 |
| Tuberin/TSC2 | 6476 | 6548 | 6549 |
| XIAP | 6446 | 6550 | 6551 |
