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Cellular Metabolism (Pathway Diagram)

Overview of Cellular Metabolism pathways, antibodies and related reagents, interactive pathway diagrams, and other technical resources

Cellular Senescence

Cellular senescence is stable cell cycle arrest linked to aging and cancer and other disease states, including those associated with inflammation. It is induced by DNA damage, oncogenic signaling, and telomere shortening.

Certifications

Cell Signaling Technology, Inc. (CST) is ISO 9001:2008 certified for the design, development, and production of monoclonal antibodies (mAbs).

CH Protein Domain (Protein Domains)

A scientific resource for the CH protein domain containing information on structure, function, and binding to phospho-serine and phospho-threonine motifs.

Changes to Recommended Western Blotting Protocols (Protocols)

A demonstration of the perils of deviating from Cell Signaling Technology's recommended protocols.

ChIP & ChIP-seq (Application Overviews)

Comprehensive SimpleChIP® kits and ChIP validated antibodies from CST and validated ChIP reagents (primer pairs, Protein G agarose and magnetic beads

ChIP Validated Antibodies and Primer Pairs (Application Overviews)

SimpleChIP® Kits and Antibodies validated in-house by our antibody development scientists correlated to positive and negative control primers.

ChIP-seq Ab Performance Comparison (Product Type Overviews)

ChIP-seq is a powerful technique that combines ChIP and next-generation sequencing (NGS) to study DNA-protein interactions across the entire genome, but it is only as good as the quality of the antibody used in the ChIP experiment.

ChIP-seq Validated Antibodies

ChIP-seq is a powerful technique that combines ChIP and next-generation sequencing (NGS) to study DNA-protein interactions across the entire genome, but it is only as good as the quality of the antibody used in the ChIP experiment.

ChIP-Sequencing performed using the SimpleChIP® Kit (Application Overviews)

Use SimpleChIP kits to perform high throughput ChIP-Sequencing and assay genome wide changes in histone modifications and transcription factor binding.

Chromatin Immunoprecipitation Technical Support (Application Overviews)

Detailed technical support information to support ChIP experimental success. LInk to CST's comprehensive ChIP protocol.

Chromatin Immunoprecipitation Troubleshooting Guide (Protocols)

Chromatin Immunoprecipitation Troubleshooting Guide: easy to follow directions describing the step by step experimental procedure.

Chromatin Immunoprecipitation Workflow Solutions for ChIP-qPCR and ChIP-seq (Application Overviews)

Chromatin Immunoprecipitation Workflow Solutions for ChIP-qPCR and ChIP-seq

Chromatin IP Frequently Asked Questions (Application Overviews)

Chromatin IP (ChIP) Frequently Asked Questions (FAQs) from Cell Signaling Technology, Inc.

Chromo Protein Domain (Protein Domains)

A scientific resource for the Chromo protein domain containing information on structure, function, and binding to methylated lysine residues during chromatin remodeling.

CK1 Protein Kinases Group (Kinome Diagram)

A kinome diagram showing the CK1 family of protein kinases.

CMGC Protein Kinases Group (Kinome Diagram)

A kinome diagram showing the CMGC group of protein kinases.

Commitment to Science

Summary description of CST with the mission statement and corporate commitment.

Commitment to the Arts

CST continues to be a strong patron of the arts with in-house galleries highlighting the work of local and regional artists.

Common Pluripotency Markers

Highlighted common pluripotency markers with a brief description of their expression from Cell Signaling Technology

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