Basket Updated
0
Items added
Our Phospho-Src Family (Tyr416) (D49G4) Rabbit mAb #6943 detects endogenous levels of human Src protein only when phosphorylated at Tyr419. The discrepancy in the product name is due to this phospho-site being first discovered and published for the chicken Src protein, which is phosphorylated at Tyr416. When this antibody was released, the Tyr416 was still the common notation, which is why we refer to this site in the product name.
Products and Related Resources for Adaptive Immune Response SARS-CoV-2 Research
Products and Related Resources for Cytokines and Inflammation SARS-CoV-2 Research
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Information and case study data for the PTMScan Direct Tyrosine Kinases Service from Cell Signaling Technology.
Expert-reviewed interactive pathway providing a current overview of ErbB/HER Signaling.
The Jak/Stat Utilization Table displays the combinatorial use of tyrosine kinases and Stat proteins in cytokine/growth factor signaling.
To study pathways regulated by nitrotyrosine, CST offers two recombinant monoclonal antibodies against the same PTM for WB and proteomic applications.
A scientific resource for the SH2 protein domain containing information on structure, function, and domain binding to phospho-tyrosine motifs.
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
Learn more about commonly used chemical modulators to study cellular physiology and biology.
Information and case study data for the PTMScan Direct PI3K/Akt Service offered by CST, which allows for targeted screening of 105 proteins within the Akt pathway.
Expert-reviewed interactive pathway providing a current overview of Inhibition of Apoptosis Signaling.
Expert-reviewed diagram providing a current overview of the m6A RNA pathway with references to its role in tumor development
Products and Related Resources for Cell Death and Viability SARS-CoV-2 Research
Overview of Adhesion and Extracellular Matrix signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources.
Products and Related Resources for Type I Interferon and Viral Restriction Factors SARS-CoV-2 Research
Illustration of Motif Antibody Coverage
Explore the G protein coupled receptor signaling pathway and its diverse roles in cellular communication. Read more here.
Expert-reviewed interactive pathway providing a current overview of T Cell Receptor (TCR) Signaling.
Explore the complex inflammation signaling pathways. Click here to learn more and understand the molecular basis of inflammation.
Expert-reviewed interactive pathway providing a current overview of Regulation of Actin Dynamics.
A scientific resource for the 14-3-3 protein domain containing information on structure, function, and binding to phospho-serine and phospho-threonine motifs.
SimpleChIP Kits and Antibodies validated in-house by our antibody development scientists correlated to positive and negative control primers.
List of publications based on primary research done by the Cancer Research Group at CST (2002-2013).
For antigenic targets where expression of the protein is very low or unknown, the use of recombinant proteins or exogenous expression in a surrogate cell line may be necessary for antibody validation.
Learn about BCR signaling and how it can lead to changes in cell metabolism, gene expression, and cytoskeletal organization. Click here.
We’ve put together a starter’s guide on the cellular mechanisms that drive neurodegeneration in diseases such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, amyotrophic lateral sclerosis, and Huntington’s disease.
This video introduces PTMScan technology, a platform for the enrichment of post-translational modifications (PTMs) in mass spectrometry-based proteomics studies.
