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The activity of genes and their regulatory elements is, in part, governed by their cell type-specific chromatin organization.
Discover the key epigenetic drivers of breast cancer and the best products to target them.
Discover the most important epigenetic markers that contribute to the progression of diffuse intrinsic pontine glioma (DIPG).
This is a four-part series featuring tips to improve your ChIP protocol.
Interact with this diagram showing the epigenetic regulators of Histone H3 including those responsible for monomethylation, asymmetric and symmetric dimethylation, and trimethylation.
CUT&Tag Frequently Asked Questions (FAQs) from Cell Signaling Technology, Inc.
Maximize your research with our CUT&RUN Kit. Streamline chromatin profiling with our efficient, user-friendly tools designed for deeper, more insightful analyses.
Learn how CUT&Tag cuts down your chromatin profiling experiment time. You’ll get the same great data with a fraction of the DNA library prep time and improved signal-to-noise.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
How can I determine the different ways a protein can affect gene expression? ChIP, CUT&RUN, & Nex-gen Sequencing. Learn how to research gene expression.
CUT&RUN Frequently Asked Questions (FAQs) from Cell Signaling Technology, Inc.
Expert-reviewed interactive pathway providing a current overview of Histone Methylation.
The Histone Modification Table provides a referenced list of many known histone modifications, associated modifying enzymes, and proposed functions.
CUT&RUN is a revolutionary technique that lets you see DNA-protein interactions in a whole new way. Identify protein binding sites at high resolution. Click
Histone modification antibodies are validated using a peptide array assay at CST
Expert-reviewed interactive pathway providing a current overview of PTM Crosstalk Signaling.
Click here to discover the intricacies of methylation pathways and their role in gene regulation and epigenetic modifications.
Listing of IHC-related scientific posters and papers involving scientists from Cell Signaling Technology.
Expert-reviewed diagram providing a current overview of the Senescence Signaling pathway with references to its role in cell cycle
In response to a variety of environmental factors, cells may permanently cease proliferation and enter a state known as cellular senescence.
Learn how RNA-binding proteins influence RNA regulation and epitranscriptomics and contribute to the progression of a variety of diseases.
A chronological listing of case studies and peer-reviewed publications utilizing PTMScan proteomic technology developed by Cell Signaling Technology.
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
A troubleshooting guide for CUT&Tag–a ChIP-seq alternative with lower sample requirements, lower sequencing cost, and improved signal-to-noise for profiling chromatin and protein-DNA interactions.
Streamline your neurodegeneration therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Stress granules are a cellular defense mechanism against stress but disruption in disassembly can lead to toxic proteins and neurodegenerative diseases.
PD is characterized by functional loss in dopaminergic neurons, believed to be caused by disruption of proteins involved in cell quality control pathways.
CUT&Tag delivers quality NGS data even if the signal from the Bioanalyzer or TapeStation System is low and the DNA library yield is low.
Peptide array assays assess reactivity against known modifications across all histone proteins in a single experiment.
