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The immune system is composed of tissues, cells, and molecules whose primary function is to detect, respond to, and eliminate pathogens and transformed cells.
This interactive guide shows the key cell and functional state markers for tumor-infiltrating immune cells in humans.Web Location: Immunology and Inflammation
CST offers a growing portfolio of products for the study of immune checkpoint targets in cancer, including several receptor-ligand pairs.
Products and Related Resources for Virus Detection and Innate Immune Activation SARS-CoV-2 Research
Use our protocol compatibility table to understand which immune signaling and phenotyping antibodies will work together in your multicolor flow cytometry experiment.
A list of important CD markers that includes links to PhosphoSitePlus, Uniprot, and products from Cell Signaling Technology.
Discover the power of flow cytometry in cellular analysis and biomarker detection. Click here to learn more
TMT10plex Proteome Analysis in Cell Lines
Lymphoma is a cancer of the lymphatic system, a key part of the body’s immune system. Treatment options & patient prognoses differ based on lymphoma type.
Expert-reviewed interactive pathway providing a current overview of Contribution of Extracellular Matrix to EMT Signaling.
Why not take advantage of our own immune system and the best of its weaponry, the T-cells, to fight cancer? This is the basis of immunotherapy.
The Histone Modification Table provides a referenced list of many known histone modifications, associated modifying enzymes, and proposed functions.
Interact with this CAR-T signaling pathway to learn how the combination of extracellular and intracellular domains, including CD8, CD28, 4-1BB, OX40, or CD27, exert antitumor effects.
Products and Related Resources for Viral Entry, Replication, and Transcription SARS-CoV-2 Research
Recent advancements including next-generation proteasome inhibitors, monoclonal bispecific antibodies, antibody-drug conjugates, and CAR-T therapies that have changed the therapeutic landscape for multiple myeloma.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Advancements in immunotherapeutics against cancer include receptor agonists, adoptive cell transfer, anti-cancer vaccines, and combination therapies.
There are a number of markers that can be used to distinguish the many cell types of the central and peripheral nervous system during development, adult neurogenesis, and the pathogenesis of neurodegenerative disorders.
Expert-reviewed interactive pathway providing a current overview of TLR signaling.
The ESC and Lineage Markers diagram provides an overview of ESC differentiation along lineage-specific pathways and links to products from CST.
Overview of Cellular Metabolism pathways, antibodies and related reagents, interactive pathway diagrams, and other technical resources
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
List of publications based on primary research done by the Cancer Research Group at CST (2002-2013).
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
Identification of ALK and ROS1 fusion proteins in non-small cell lung cancer (NSCLC) at Cell Signaling Technology.
Streamline your neurodegeneration therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Expert-reviewed interactive pathway providing a current overview of PTM Crosstalk Signaling.
