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CST offers a growing portfolio of products for the study of immune checkpoint targets in cancer, including several receptor-ligand pairs.
Products and Related Resources for Fibrosis SARS-CoV-2 Research
Interact with this signaling pathway showing immune checkpoint regulation in the tumor microenvironment, including targets such as PD-L1, GITR, TIM-3, CTLA-4, OX40, and more.
This interactive guide shows the key cell and functional state markers for tumor-infiltrating immune cells in humans.Web Location: Immunology and Inflammation
Products and Related Resources for Adaptive Immune Response SARS-CoV-2 Research
Products and Related Resources for Virus Detection and Innate Immune Activation SARS-CoV-2 Research
Why not take advantage of our own immune system and the best of its weaponry, the T-cells, to fight cancer? This is the basis of immunotherapy.
This interactive guide shows the most important cell and functional state markers for tumor-infiltrating immune cells in mice.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Metabolic processes regulate immune cell function in a process known as immunometabolism, which can be studied using these macrophage and T-cell markers.
Use our protocol compatibility table to understand which immune signaling and phenotyping antibodies will work together in your multicolor flow cytometry experiment.
Expert-reviewed interactive pathway providing a current overview of Contribution of Extracellular Matrix to EMT Signaling.
The Histone Modification Table provides a referenced list of many known histone modifications, associated modifying enzymes, and proposed functions.
A list of important CD markers that includes links to PhosphoSitePlus, Uniprot, and products from Cell Signaling Technology.
The ESC and Lineage Markers diagram provides an overview of ESC differentiation along lineage-specific pathways and links to products from CST.
List of publications based on primary research done by the Cancer Research Group at CST (2002-2013).
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
Scientific posters presented by CST scientists at various conferences and trade shows through the years.
Multiplex IHC - Being able to visualize multiple targets simultaneously is important in research fields like immunology & oncology. Learn more here.
How do you design a panel of antibodies and fluorophores for mIHC? Learn how to set up a protocol that avoids epitope masking by optimizing antibody order.
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
SignalStar™ Spatial Profiling is a revolutionary new tool for spatial biology research with fully customizable and highly-validated antibody IHC panels.
The immune system is composed of tissues, cells, and molecules whose primary function is to detect, respond to, and eliminate pathogens and transformed cells.
Explore the complex inflammation signaling pathways. Click here to learn more and understand the molecular basis of inflammation.
This application note can help you optimize dual staining of mouse CD8 and FoxP3 on the Leica Bond autostainer.
The D8L9T CD36 clone from CST (# 14347) exhibits superior sensitivity and specificity by IHC and Western blot when compared to a CD36 clone from an alternative vendor.
Immunophenotyping is a technique that uses antibodies to allow the identification and quantification of particular cell types within a heterogenous population.
Immunohistochemical Analysis. Learn the best ways to interpret IHC staining and understand experimental results accurately. Click here.
