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Catalog numbers in tabular format for control cell extracts and proteins with links to product pages.
A scientific resource for the 14-3-3 protein domain containing information on structure, function, and binding to phospho-serine and phospho-threonine motifs.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
Information and case study data for the PTMScan Direct PI3K/Akt Service offered by CST, which allows for targeted screening of 105 proteins within the Akt pathway.
Explore the mitochondrial apoptosis pathway and its role in programmed cell death. Read more about this essential pathway here.
Overview of apoptosis signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources for apoptosis research.
A scientific resource for the PTB protein domain containing information on structure, function, and domain binding to phospho-tyrosine motifs.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Responsible Science Podcast: Episode 4 - Publishing
Information and case study data for the PTMScan Direct Apoptosis/Autophagy Service offered by CST.
A scientific resource for the BH protein domains containing information on structure, function, and domain binding in apoptosis.
Which plasma biomarkers could be used to accurately predict the severity of Alzheimer's Disease (AD) progression in patients?
Products and Related Resources for Cytokines and Inflammation SARS-CoV-2 Research
The three main purposes of metabolism are the conversion of food to energy; the conversion of nutrients to proteins, carbohydrates, lipids, and nucleic acids; and the elimination of nitrogenous wastes. There is a strong correlation between metabolic chan
Products and Related Resources for Type I Interferon and Viral Restriction Factors SARS-CoV-2 Research
Expert-reviewed interactive pathway providing a current overview of Inhibition of Apoptosis Signaling.
Products and Related Resources for Virus Detection and Innate Immune Activation SARS-CoV-2 Research
PTMScan Motif Antibodies and Kits, for customers who purchase a license and would like to perform PTMScan Proteomics in-house.
PTMScan Motif Antibody Kits from Cell Signaling Technology
Study the intricate machinery of the apoptosis signaling pathway. Click here to learn more and gain insights into programmed cell death mechanisms.
Products and Related Resources for Adaptive Immune Response SARS-CoV-2 Research
Abnormal cell-cell communication, for example disrupted presynaptic input, as well as disrupted intracellular signaling contribute to the pathogenesis of neurodegenerative disease.
We’ve put together a starter’s guide on the cellular mechanisms that drive neurodegeneration in diseases such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, amyotrophic lateral sclerosis, and Huntington’s disease.
Phospho-Erk product lists, product citation lists, product selection tools, comparison tables and educational resources for MAPK signaling from Cell Signaling Technology.
Phospho-GSK-3β antibodies that detect phosphorylation at Ser9 upon activation in properly treated samples are also capable of detecting the GSK-3β-Tag. Although these antibodies are specific to the Ser9 site of GSK-3β, the GSK-3β-Tag is quite similar to their antigen sequences. CST offers the following phospho-GSK-3β (Ser9) antibodies which also detect the GSK-3β-Tag: Phospho-GSK-3β (Ser9)(D85E12) XP® Rabbit mAb #5558Phospho-GSK-3β (Ser9)(5B3) Rabbit mAb #9323Phospho-GSK-3β (Ser9)(D2Y9Y) Mouse mAb #14630Phospho-GSK-3β (Ser9) Antibody) #9336
Our summary of recent findings published in Nature, which indicate that non-performing antibodies were used in many recent macular degeneration studies.
Discover the PI3K Akt pathway and its crucial role in cell growth and survival. Click here to learn more & gain insights into this important signaling cascade
Compare Cell Signaling Technology's Akt antibodies against one another to determine optimal applications
Our Phospho-Akt (Thr308) (C31E5E) Rabbit mAb #2965 detects over-expressed levels of PKCalpha and beta. It also detects endogenous levels of PKC in Jurkat + CalA extract and possibly weakly in other endogenous models tested. Our Phospho-Akt (Thr308) (L32A4) Mouse mAb #5106 and Phospho-Akt (Thr308) Antibody #9275 detect over-expressed levels of PKCalpha and beta, but do not detect endogenous PKC. Our Phospho-Akt (Thr308) (244F9) Rabbit mAb #4056 detects over-expressed levels of PKCalpha and beta and may also weakly detect endogenous PKC in Jurkat + CalA extract, but not in other endogenous models tested. Our Phospho-Akt (Thr308) (D25E6) XP Rabbit mAb #13038 does not detect over-expressed PKC and is the best choice of the Phospho-Akt (Thr308) antibodies if this is a concern.
