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CAR Signaling Networks Interactive Pathway (Pathway Diagram)

Interact with this CAR-T signaling pathway to learn how the combination of extracellular and intracellular domains, including CD8, CD28, 4-1BB, OX40, or CD27, exert antitumor effects.

Control Treatments by Target (Control Table)

A list of recommended cell types and treatments to be used as positive and negative controls for activation state specific antibodies

Protocol Compatibility Table for Immune Signaling and Phenotyping by Flow Cytometry (Table Resources)

Use our protocol compatibility table to understand which immune signaling and phenotyping antibodies will work together in your multicolor flow cytometry experiment.

Immunology/Inflammation (Pathway Diagram)

Expert-reviewed interactive pathways providing current overviews of NF-kB and Toll-like Receptor (TLR) signaling, as well as links to products from Cell Signaling Technology.

Kinase Signaling (Pathway Diagram)

Expert-reviewed interactive pathway providing a current overview of ErbB/HER Signaling, a pathway description, select PubMed references, and links to PhosphoSitePlus.

Kinase-Disease Associations (Table Resources)

Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.

Protein and Pathway Abbreviations (Table Resources)

Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.

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