RNA Regulation, Epitranscriptomics, and Disease | Cell Signaling Technology
KinomeView® Protocol: easy to follow directions describing the step by step experimental procedure.
In-Cell Western Protocol: easy to follow directions describing the step by step experimental procedure.
In-cell Western: a simple method for quantification of intracellular signaling in whole cells. Data and links for tech support.
ELISA Protocol for PathScan® Stress and Apoptosis Signaling Antibody Array Kit (Fluorescent Readout) #12923: easy to follow directions describing the step by step experimental procedure.
Organelle markers for immunofluorescence analysis from CST Cell Signaling Technology
There are a number of markers that can be used to distinguish the many cell types of the central and peripheral nervous system during development, adult neurogenesis, and the pathogenesis of neurodegenerative disorders.
Neuroinflammation is the activation of an immune response in the CNS by the microglia and astrocytes. While not linked mechanistically to neurodegenerative diseases, neuroinflammation is associated with the progression of Alzheimer's disease, Parkinson's
Metabolism defines all of the chemical changes or processes within cells, tissues, and organisms that sustain cellular homeostasis.
Cellular senescence is stable cell cycle arrest linked to aging and cancer and other disease states, including those associated with inflammation. It is induced by DNA damage, oncogenic signaling, and telomere shortening.
Trademark information appearing on Cell Signaling Technology website.
Western blotting using fluorescent-conjugated secondary antibodies - accurate quantification and two-color multiplexing using primary antibodies from different species.
Modulation of CNS function occurs through synaptic neurotransmission, which is the signaling from the axon terminal of one neuron to the dendrites of another via molecules called neurotransmitters.
Custom antibody conjugation services are available for our antibody catalog. Services include conjugation to a variety of fluorophores, beads, biotin, and HRP.