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Information and case study data for the PTMScan Direct PI3K/Akt Service offered by CST, which allows for targeted screening of 105 proteins within the Akt pathway.
Information and case study data for the PTMScan Direct Tyrosine Kinases Service from Cell Signaling Technology.
A scientific resource for the WW protein domain containing information on structure, function, and domain binding to proline-rich motifs.
A scientific resource for the HECT protein domain containing information on structure, function, and domain binding in ubiquitin-mediated protein degradation.
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
Cell Signaling Technology, Inc. (CST) of Danvers, MA, announced today that it has introduced a highly specific PD-L1 rabbit monoclonal antibody (mAb).
Study the intricate Notch signaling pathway and its impact on cell fate determination and development. Click here to learn more.
Dako and Cell Signaling Technology (CST) today announced that they have entered into a strategic partnership to supply antibodies for use in Dako-branded companion diagnostics products.
Information and case study data for the PTMScan Direct Cell Cycle and DNA Damage Service offered by CST.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
Study the ubiquitin proteasome pathway and its critical role in protein degradation and cellular homeostasis. Expert reviewed pathways.
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
Expert-reviewed interactive pathway providing a current overview of protein ubiquitination and proteasome degradation, as well as links to products from Cell Signaling Technology.
Cell Signaling Technology, Inc. (CST) is ISO 9001:2008 certified for the design, development, and production of monoclonal antibodies (mAbs).
UbiScan® - Ubiquitination Proteomics
We have no specific tips for using FACS-isolated cells in CUT&RUN experiments. Like a cultured cell suspension, if your isolated cells are in less than 40ul PBS, you can move directly to Concanavalin A bead binding by adding wash buffer for a total of 100ul per reaction. Otherwise, you need to either spin the cells and remove some of the PBS or add wash buffer and Concanavalin A beads proportionally based on the volume of PBS you have in your sorted cell sample. In our experience, the Concanavalin A beads do not bind to cells in the pure PBS environment.
Cell Signaling Technology, a leading provider of antibodies, kits and services, announced today that it has won two Life Science Industry Awards® for "Best Antibodies" and "Most Useful Website."