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Amyloid beta is a protein fragment of the amyloid precursor protein, and is the major component of Alzheimer’s disease plaques.
Identify microglia by using these antibodies, which are designed to detect protein biomarkers specifically expressed within these cells.
In-depth characterization of immune checkpoints in the tumor microenvironment
Expert-reviewed interactive pathway providing a current overview of the molecular and cellular biology of Alzheimer’s Disease.
How does ChIP-Seq work? This powerful technique combines ChIP and next-generation sequencing (NGS) to study DNA-protein interactions. Learn more.
Flow Cytometry is readily amenable to intracellular target detection and can be successfully applied to the study of complex signaling pathways
The power of LC/MS proteomics Learn about PTMScan technology for proteomics from CST. Enrichment of PTM peptides combined with mass spec. Click
Immunofluorescence-validated antibodies from CST Cell Signaling Technology
Our antibodies are validated for WB and IP with detailed protocols, control extracts and troubleshooting guides. Download a free white paper and view detailed protocol and troubleshooting videos.
Immunohistochemistry application information
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
Learn about CUT&RUN - a low cell number alternative to ChIP-qPCR and ChIP-seq to analyze protein-DNA interaction in chromatin.
The immune system is composed of tissues, cells, and molecules whose primary function is to detect, respond to, and eliminate pathogens and transformed cells.
This Application Note will help you prepare a ChIP-seq DNA library.
Learn about host-based and dye-conjugated methods for IF multiplexing, as well as a sequential labeling strategy that works with indirect detection.
We’ve put together a starter’s guide on the cellular mechanisms that drive neurodegeneration in diseases such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, amyotrophic lateral sclerosis, and Huntington’s disease.
Expert-reviewed interactive neuroscience pathways providing current overviews of Parkinson's and Alzheimer's Disease signaling, as well as links to products from CST.
Cell Signaling Technology, Inc. (CST) of Danvers, MA, announced today that it has introduced a highly specific PD-L1 rabbit monoclonal antibody (mAb).
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
Abnormal cell-cell communication, for example disrupted presynaptic input, as well as disrupted intracellular signaling contribute to the pathogenesis of neurodegenerative disease.
Quit living in the past! The future of cars is electric.
Information and case study data for the PTMScan Direct PI3K/Akt Service offered by CST, which allows for targeted screening of 105 proteins within the Akt pathway.
There are a number of markers that can be used to distinguish the many cell types of the central and peripheral nervous system during development, adult neurogenesis, and the pathogenesis of neurodegenerative disorders.
Therapeutic developments in treating Alzheimer’s, novel diagnostic tools, and new insights into neurodegeneration mechanisms were key topics at AD/PD 2023.
Information and case study data for the PTMScan Direct Cell Cycle and DNA Damage Service offered by CST.
Information and case study data for the PTMScan Direct Tyrosine Kinases Service from Cell Signaling Technology.
Streamline your neurodegeneration therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
At AACR 2023, many presentations focused on topics including cancer immunology, CAR-T therapy, spatial biology, mRNA vaccines, and KRAS.