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Resources results for "TOP2A iso2"

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PTMScan® PI3K/Akt Signaling

Information and case study data for the PTMScan Direct PI3K/Akt Service offered by CST, which allows for targeted screening of 105 proteins within the Akt pathway.

PTMScan® Tyrosine Kinase

Information and case study data for the PTMScan Direct Tyrosine Kinases Service from Cell Signaling Technology.

PTMScan® Direct Cell Cycle & DNA Damage

Information and case study data for the PTMScan Direct Cell Cycle and DNA Damage Service offered by CST.

Matched Antibody Pairs

Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.

G2M/DNA Damage Checkpoint

Expert-reviewed interactive pathway providing a current overview of Cell Cycle G2/M DNA Damage Signaling.

Cell Cycle Regulation

Study the intricate cell cycle pathway's regulation of cell division and proliferation. Learn more here.

Cell Signaling Technology® Products are Prevalent in CiteAb's Top Antibodies of 2022

Cell Signaling Technology® products are prevalent in CiteAb's Top Antibodies of 2022 with 9 of the top 10 most cited primary antibodies from CST.

Antibody Validation for SignalStar™ Multiplex IHC

ELISA Protocol - Specific For Product: 12856

ELISA Protocol for PathScan Stress and Apoptosis Signaling Antibody Array Kit: easy to follow directions describing the step by step experimental procedure.

Application-Specific Antibody Validation: Finding an IHC-Validated Claudin-6 mAb

Finding an IHC-Validated Claudin-6 mAb. Learn how CST scientists apply rigorous, application-specific validation methods to the development of antibodies.

Immuno-Parallel Reaction Monitoring (iPRM)

iPRM is a multiplexed LC/MS assay service that combines the specificity of mass spectrometry, the throughput of an immunoassay, and the power of multiplexing to accelerate the time-to-market of your drug and/or diagnostic test.

PI3K / Akt Substrates Table

The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.

Antibody Validation for Immunohistochemistry

An outline and examples of the steps performed at Cell Signaling Technology to validate target specificity of an antibody for use in immunohistochemical analysis.

FH2 Protein Domain

A scientific resource for the FH2 protein domain containing information on structure, function, and domain binding to actin.

WD40 Protein Domain

A scientific resource for the WD40 protein domain containing information on structure, function, and binding to both phospho-Ser/Thr and methylated lysine residues.

ELISA Protocol - Specific For Product: 12923

ELISA Protocol for PathScan Stress and Apoptosis Signaling Antibody Array Kit: easy to follow directions describing the step by step experimental procedure.

Prostate Cancer

Discover the top epigenetic markers that you should look out for in prostate cancer research.

Immunohistochemistry (IHC) Troubleshooting Guide & the Importance of Using Controls

Eliminate non-specific binding and high background with the immunohistochemitry (IHC) troubleshooting guide and positive/negative controls

Immunohistochemistry Protocol - Paraffin for SignalStain® Boost Detection Reagent

Immunohistochemistry Protocol - Paraffin for Boost Detection Reagent: easy to follow directions describing the step by step experimental procedure.

CST Media Room

CST Media Room

How to Accurately Count Cells Manually or with an Automated Cell Counter

Cell counting is essential for monitoring cell health and proliferation. Learn how to count accurately and determine cell density and percent viability.

Altered Cell Signaling

Abnormal cell-cell communication, for example disrupted presynaptic input, as well as disrupted intracellular signaling contribute to the pathogenesis of neurodegenerative disease.

Fluorescent Multiplex Immunohistochemistry (mIHC) with Tyramide Signal Amplification Protocol

mIHC with tyramide signal amplification protocol. Detect and localize multiple proteins in tissue sections simultaneously. Click here to learn more.

Resources

The methods for the LC and MS are shown below:
 

 ParameterSetting
Sample prepIP sample resuspension volume20 uL
 Sample volume per injection4 uL
 

MEDx and CST Expand Partnership for Companion Diagnostic (CDx) Development for the Chinese Market

MEDx and CST announce expansion of their ongoing partnership for companion diagnostic (CDx) development using CST® antibodies to meet growing demand in China.

CST’s Cell Cyclers Take Third Place in Statewide Bike to Work Week

Bay State Bike Week and the Mass Commute Bicycle Challenge is a great event to promote cycling and build community spirit. CST is looking forward to Bike Week next year where we hope to break the 2,100 mile mark!

How to Control Your Apoptosis, Autophagy, and Mitophagy Western Blots

Find out the best control cell extracts to use as positive or negative controls in your western blots, when studying apoptosis, autophagy, and mitophagy.

Every Day is Earth Day at Cell Signaling Technology

The top 5 ways that CST acts to make every day Earth Day.

Resources

The top band in the gel image for our Human ACE2 (18-652) Recombinant Protein (mFc-Tag) #83986 likely represents dimerization due to the mFc tag.

AD/PD 2023: Therapeutics, Diagnostics & Mechanisms Linked to a Classic Alzheimer’s Disease Theory

Therapeutic developments in treating Alzheimer’s, novel diagnostic tools, and new insights into neurodegeneration mechanisms were key topics at AD/PD 2023.