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PTMScan Motif Antibody Kits from Cell Signaling Technology
Discover the PI3K Akt pathway and its crucial role in cell growth and survival. Click here to learn more & gain insights into this important signaling cascade
PTMScan® Sumoylation Remnant Motif Kit - SUMOylation Proteomics
CST® Proteomics Analytical Services help you identify and validate drug targets, discover biomarkers, determine on/off-target effects, and mechanisms of action.
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.
Expert-reviewed diagram providing a current overview of the Mechanisms of Fibrosis pathway with references to its role in adhesion
Mutations in cell death pathways, such as apoptosis, mitophagy, necroptosis, and autophagy, contribute to neuronal cell death and the progression of neurodegenerative diseases.
Summary of human oncogenes and tumor suppressor genes sorted by signaling pathway.
When designing an antibody panel for multiplex IHC, it’s important to optimize each antibody’s dilution and which fluorophore it’s paired with. This will help your staining achieve a balanced set of signals.
A table that lists shelf-life expectations for CST products (when stored under the recommended conditions).
Phosphorylation and ubiquitylation events are of interest in preclinical investigations of cancer. This webinar considers study design for label-free mass spectroscopy analysis, enrichment strategies, and data analysis.
Necrosis has been classically defined as an unprogrammed form of cell death that occurs in response to overwhelming chemical or physical insult.
The ESC and Lineage Markers diagram provides an overview of ESC differentiation along lineage-specific pathways and links to products from CST.
Expert-reviewed diagram providing a current overview of the m6A RNA pathway with references to its role in tumor development
Streamline Targeted Protein Degradation Drug Discovery with specific, application-validated antibodies and industry-leading proteomic services.
Fostering mentorship, application-based learning, and a love of science are all part of the mission of the CST internship program. Students interning with us are partnered with CST Mentors.
Cellular senescence is characterized by irreversible cell-cycle arrest in combination with a distinct secretory phenotype and expanded lysosomes in response to stress. Senescent cells accumulate in tissues during aging, and various markers of senescence
Resources include signaling pathways, antibodies and companion products, research overviews, technical resources, and recent review articles.