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May 2012, Discovery platform is developed for antigen-specific monoclonal antibodies named NG-XMT(TM).
Jan 2013, CST granted patent for PCR Methods for detection of a subset of treatable non-small cell lung cancers.
Stress granules are a cellular defense mechanism against stress but disruption in disassembly can lead to toxic proteins and neurodegenerative diseases.
Nov 2007, CST was awarded LEED(R) Certification by the U.S. Green Building Council (USGBC).
We have committed to donating 1% of our total annual revenue to environmental giving in collaboration with 1% for the Planet. Join the movement.
Use SimpleChIP kits to perform high throughput ChIP-Sequencing and assay genome wide changes in histone modifications and transcription factor binding.
Flow Cytometry Protocol for FoxP3 on Murine Splenocyte T Cells: easy to follow directions describing the step by step experimental procedure.
To perform intracellular flow cytometry, fixation and permeabilization of cells is required to allow for antibody penetration and subsequent binding to targets without disrupting cellular morphology.
Cell behavior is a tightly regulated process where various signals work together to elicit a specific response. Unraveling these mechanisms allows us to understand how cells are regulated in a normal state.
Troubleshooting tips for successfully performing Intracellular Flow Cytometry using CST recommended protocols and antibodies validated for Flow.
Writing an abstract — condensing your information into 200 words — is daunting. This post outlines the steps to draft an abstract tailored to the journal you want.
CST donates lab equipment to Seeding Labs, a non-profit helping scientists in developing countries. Read the interview with Dr. Lillianfeld to learn more.
In the CUT&RUN kit protocol, the addition of digitonin to the buffers facilitates the permeabilization of cell membranes & the entry of the primary antibody & pAG-MNase enzyme into the cells & nuclei.
March 2011, Ventana Medical Systems, granted a worldwide non-exclusive license to CST patent rights and proprietary antibody reagents relating to the detection of epidermal growth factor receptor (EGFR) mutations for the field of tissue-based in vitro diagnostic testing.
Therapeutic developments in treating Alzheimer’s, novel diagnostic tools, and new insights into neurodegeneration mechanisms were key topics at AD/PD 2023.
Intracellular flow cytometry enables characterization of signaling networks at a single cell level in phenotypically distinct cell populations.
Validated antibodies for high content screening from CST Cell Signaling Technology
A scientific resource for the SH2 protein domain containing information on structure, function, and domain binding to phospho-tyrosine motifs.
Cell Signaling Technology, Inc. Announces License in Personalized Cancer Diagnostics.
A scientific resource for the PTB protein domain containing information on structure, function, and domain binding to phospho-tyrosine motifs.
A scientific resource for the PWWP protein domain containing information on structure, function, and domain binding.
Roughly 1 in 8 men will be diagnosed with prostate cancer. So why do so many men lose their battle? Emerging therapeutic options may turn this around.
Happy Thanksgiving from CST.
A scientific resource for the TIR protein domain containing information on structure, function, and binding in TLR Signaling.
Flow Cytometry (F) Protocol for the Detection of Transcription Factors with recommended companion products.
Cell Signaling Technology, Inc. (CST) of Danvers, MA, announced today that it has introduced a highly specific PD-L1 rabbit monoclonal antibody (mAb).
Identifying and quantifying myeloid subtypes is essential for understanding why different cell populations are activated in response to certain pathogens.
Expert-reviewed interactive pathway providing a current overview of Vesicle Trafficking Presynaptic Signaling.
A scientific resource for the coiled coil (CC) protein domain containing information on structure, function, and domain binding.
A scientific resource for the Chromo protein domain containing information on structure, function, and binding to methylated lysine residues during chromatin remodeling.