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细胞焦亡与其他多种细胞程序性死亡形式之间存在相互联系和转化,共同构成细胞程序性死亡的复杂体系,维持细胞和机体的内稳态。
CST Technical Support Article
CST promotes alternative transportation through a variety of programs.
本场讲座将逐一介绍多种细胞程序性死亡(凋亡、自噬、程序性坏死、细胞焦亡)相关信号通路关键蛋白和研究策略,并就多种细胞程序性死亡形式之间的联系和转化展开讨论,为大家全面认识细胞程序性死亡和开展系统研究提供参考。
The California Supply Chains Act requires CST to disclose its current practices to combat slavery and human trafficking in five specific areas.
本次研讨会将通过介绍CST Western Blot标准操作步骤,向您阐释WB操作中的关键点及注意事项,特别是影响最终结果呈现的样本制备和抗体孵育与检测。通过真实失败案例,如无信号、高背景、条带大小不正确、条带弯曲拖尾等,分析WB常见的问题及原因,并提供相应的解决策略。
该视频重点介绍肿瘤免疫微环境相关的主要参与细胞、调节分子和信号通路,并为各位听众提供在上述领域的主要评价指标和新的研究方法作为参考。
Products and Related Resources for Cytokines and Inflammation SARS-CoV-2 Research
Crystals may be present in our Cell Lysis Buffer (10X) #9803 upon arrival due to the high concentrations of reagents included at the supplied 10X formulation, even when warmed to room temperature. This is not a cause for concern as your buffer is still good to use. We recommend warming the buffer to 37C for 5-10 minutes with mixing to help solubilize the crystals. Alternatively, diluting the 10X solution with ddH2O to at least 5X will yield a crystal-free solution. Once diluted, it can be aliquoted and stored at -20C for future use.
Yes, you can use BSA #9998 as a carrier for cytokines. It should be dissolved into 1X PBS and sterile filtered.
The IFN-α (6B18) Mouse mAb #3110 and IFN-α (8C21) Mouse mAb #3115 antibodies are different clones to the same target. These antibodies are approved for use with recombinant protein and will not detect endogenous levels of IFN-α. While either antibody will work well, #3110 is slightly stronger than #3115 by western blot and in addition has some citations in CiteAb.
CST has an energy management plan to reduce our use of resources.
该视频将重点介绍与细胞骨架、细胞基质动态调控及EMT相关的主要调节分子和信号通路,并为各位听众提供在上述领域的主要评价指标作为参考。
CST’s does not ship in styrofoam coolers and packaging materials are recyclable.
Learn about the history of Cell Signaling Technology and our commitment to providing reproducible tools to move your science forward.
Drs. Schietinger and Youngblood review the underlying mechanisms and epigenetic programs determining tumor-specific T-cell dysfunction and reprogrammability and discuss current challenges and outstanding research questions in cancer immunotherapy.
Cigall Kadoch PhD keeps a running list of targets to advance mechanistic studies of human disease. Here, Dr. Kadoch discusses the value of collaborating with CST to develop novel reagents to probe ATP-dependent chromatin remodeling complexes.
Infiltrating myeloid cells are analyzed in the tumor microenvironment using multiplex IHC, employing new monoclonal antibodies to IDO1 and Arginase.
Products and Related Resources for Viral Entry, Replication, and Transcription SARS-CoV-2 Research