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Autophagy is more than just the bulk degradation of intracellular components. It can also selectively degrade specific organelles, pathogens, and proteins.
Mitophagy is a well-studied example of selective autophagy. This post explores mitophagy functions and the consequence of excessive or inadequate mitophagy
PTMScan Motif Antibody Kits from Cell Signaling Technology
Discover the PI3K Akt pathway and its crucial role in cell growth and survival. Click here to learn more & gain insights into this important signaling cascade
PTMScan® Sumoylation Remnant Motif Kit - SUMOylation Proteomics
CST® Proteomics Analytical Services help you identify and validate drug targets, discover biomarkers, determine on/off-target effects, and mechanisms of action.
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.
Expert-reviewed diagram providing a current overview of the Mechanisms of Fibrosis pathway with references to its role in adhesion
Mutations in cell death pathways, such as apoptosis, mitophagy, necroptosis, and autophagy, contribute to neuronal cell death and the progression of neurodegenerative diseases.
Summary of human oncogenes and tumor suppressor genes sorted by signaling pathway.
When designing an antibody panel for multiplex IHC, it’s important to optimize each antibody’s dilution and which fluorophore it’s paired with. This will help your staining achieve a balanced set of signals.
CST Technical Support Articles
Overview of PI3K/Akt signaling pathways, antibodies and related reagents, interactive pathway diagrams, and other technical resources.
A table that lists shelf-life expectations for CST products (when stored under the recommended conditions).
Fill out the form to contact the Proteomics Analytical Services team.
Phosphorylation and ubiquitylation events are of interest in preclinical investigations of cancer. This webinar considers study design for label-free mass spectroscopy analysis, enrichment strategies, and data analysis.
Necrosis has been classically defined as an unprogrammed form of cell death that occurs in response to overwhelming chemical or physical insult.
The ESC and Lineage Markers diagram provides an overview of ESC differentiation along lineage-specific pathways and links to products from CST.