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An outline and examples of the steps performed at Cell Signaling Technology to validate target specificity of an antibody for use in immunohistochemical analysis.
Cell Signaling Technology Chief Scientific Officer, Dr. Roby Polakiewicz, to Speak on Two Panels at the Global Biological Standards Institute (GBSI) Antibody Validation Workshop
The guarantee behind all of CST's antibody products, ensuring performance, lot-to-lot consistency, and application validation.
Cancer cells can resist death. They evade apoptosis, the mechanism that programs cell death once cells become damaged. Normally, apoptosis helps keep an organism healthy through growth and development, but cancer cells do not follow this process, no matter how abnormally they grow.
The Corporate Social Responsibility of Cell Signaling Technology, Inc.
Our antibodies are validated for WB and IP with detailed protocols, control extracts and troubleshooting guides. Download a free white paper and view detailed protocol and troubleshooting videos.
Cell Signaling Technology (CST), a worldwide provider of antibodies, participated in the 2016 Global Biological Standards Institute (GBSI) Antibody Validation: Standards, Policies and Practices Workshop
Finding an IHC-Validated Claudin-6 mAb. Learn how CST scientists apply rigorous, application-specific validation methods to the development of antibodies.
Find out the best control cell extracts to use as positive or negative controls in your western blots, when studying apoptosis, autophagy, and mitophagy.
Tips on how to craft an effective elevator pitch and adapt the pitch for networking in an online world.
Annual grant application guidelines and project description criteria for funding from CST.
PD-L1/PD1 immune checkpoint helps tumor cells evade detection by the immune system. Highly specific and sensitive PD-L1 antibody now available from CST.
Download the Antibody Staining Guide for Flow Cytometry to help demystify the antibody staining process and guide you through assay set-up step-by-step.
Responsible Science Podcast: Episode 4 - Publishing
The power of LC/MS proteomics Learn about PTMScan technology for proteomics from CST. Enrichment of PTM peptides combined with mass spec. Click
Immunofluorescence-validated antibodies from CST Cell Signaling Technology
Learn about CUT&RUN - a low cell number alternative to ChIP-qPCR and ChIP-seq to analyze protein-DNA interaction in chromatin.
The privacy policy currently in place from Cell Signaling Technology, Inc.
These five organizations received donations as part of our annual global giving program at CST, one of many ways we help the impoverished and underserved.
Links to sample preparation protocols: provided in pdf format (9-15 page documents).
Autophagy is more than just the bulk degradation of intracellular components. It can also selectively degrade specific organelles, pathogens, and proteins.
SimpleChIP Kits and Antibodies validated in-house by our antibody development scientists correlated to positive and negative control primers.
Immunohistochemistry application information
DIY conjugation kits let researchers label an antibody themselves but lengthy protocols, poor conjugate quality and low yield cause inconsistent results.
Networking is an important part of any research career but can cause anxiety for many. These tips will help you prepare and make the process more enjoyable
CUT&Tag delivers quality NGS data even if the signal from the Bioanalyzer or TapeStation System is low and the DNA library yield is low.
Meet the aspiring young scientists who won the 4th annual Rising Black Scientists Awards essay competition.
Resources for CUT&Tag–a ChIP-seq alternative with lower sample requirements, lower sequencing cost, and improved signal-to-noise for profiling chromatin and protein-DNA interactions
Nov 2007, CST was awarded LEED(R) Certification by the U.S. Green Building Council (USGBC).