Resources results for "CD4"

CD Markers

A list of important CD markers that includes links to PhosphoSitePlus, Uniprot, and products from Cell Signaling Technology.

Pre-Clinical IHC Tools for Mouse Models

Pre-Clinical IHC Tools for Mouse Models

Mouse Immune Cell Marker Guide

This interactive guide shows the most important cell and functional state markers for tumor-infiltrating immune cells in mice.

Uses of Intracellular Flow Cytometry

Learn more about how intracellular flow cytometry can be used to measure unique signaling events to do with apoptosis, pluripotency status and epigenetic activity.

Overview of Immunology

The immune system is composed of tissues, cells, and molecules whose primary function is to detect, respond to, and eliminate pathogens and transformed cells.

Targeting TIGIT for Immunotherapy and T Cell Exhaustion

Given the limited but remarkable success of immune checkpoint blockade, recent efforts have been focused on identifying new targets for improving immunotherapy effectiveness in the immunosuppressive tumor microenvironment. One such target is T cell immunoreceptor with Ig and ITIM domains (TIGIT).

Advantages of Intracellular Flow Cytometry

Protocol Compatibility Table for Immune Signaling and Phenotyping by Flow Cytometry

Use our protocol compatibility table to understand which immune signaling and phenotyping antibodies will work together in your multicolor flow cytometry experiment.

Interrogating Immnunometabolism in the TME Using a Metabolic Checkpoint

Metabolic processes regulate immune cell function in a process known as immunometabolism, which can be studied using these macrophage and T-cell markers.

T Cell Signaling and Immunophenotyping

T cells are essential to cell-mediated immunity. Recognition of an antigen and engagement of a variable T cell receptor that is expressed on the cell surface leads to T cell activation.

Immune Checkpoint Signaling in the Tumor Microenvironment

Interact with this signaling pathway showing immune checkpoint regulation in the tumor microenvironment, including targets such as PD-L1, GITR, TIM-3, CTLA-4, OX40, and more.

T Cell Basics: What a Disease Researcher Needs to Know

This post explores common T cell types, their roles in modulating immune cell response, and T cell activation via interaction with cell surface receptors.

Solutions for Oncology Therapeutics Discovery

Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.

B Cell Signaling and Immunophenotyping

B cells are lymphocytes that are an important part of the humoral immune response. The main role of B cells is to produce antibodies in response to antigens.

Neural and Glial Cell Markers

There are a number of markers that can be used to distinguish the many cell types of the central and peripheral nervous system during development, adult neurogenesis, and the pathogenesis of neurodegenerative disorders.