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Information and case study data for the PTMScan Direct Cell Cycle and DNA Damage Service offered by CST.
Expert-reviewed interactive pathway providing a current overview of Cell Cycle G2/M DNA Damage Signaling.
A scientific resource for the WD40 protein domain containing information on structure, function, and binding to both phospho-Ser/Thr and methylated lysine residues.
Expert-reviewed interactive pathway providing a current overview of Cell Cycle G1/S Checkpoint Signaling.
Study the intricate cell cycle pathway's regulation of cell division and proliferation. Learn more here.
Expert-reviewed interactive pathway providing a current overview of SAPK/JNK Signaling.
A scientific resource for the POLO-Box protein domain containing information on structure, function, and domain binding to phospho-Ser/Thr motifs.
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
Discover the TGF Beta signaling pathway and impact on cell growth & tissue homeostasis. Learn here the mechanisms behind this vital signaling cascade.
Expert-reviewed interactive pathway providing a current overview of Regulation of Actin Dynamics.
The Akt Binding Partners Table provides a list of proteins that bind to Akt along with their effects, activities, and corresponding PubMed reference(s).
Expert-reviewed interactive signaling pathways providing current overviews of the regulation of actin and microtubule dynamics, as well as links to products from CST.
Checkpoint inhibitors, targeted antibodies, adoptive cell therapy, and cancer vaccines are promising immunotherapies with recent therapeutic developments.
Necrosis has been classically defined as an unprogrammed form of cell death that occurs in response to overwhelming chemical or physical insult.
Expert-reviewed signaling pathway providing a current overview of adherens junction dynamics and links to products by Cell Signaling Technology.
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
Explore the G protein coupled receptor signaling pathway and its diverse roles in cellular communication. Read more here.
Expert-reviewed interactive pathway providing a current overview of T Cell Receptor (TCR) Signaling.
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
Study the ubiquitin proteasome pathway and its critical role in protein degradation and cellular homeostasis. Expert reviewed pathways.
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.
A chronological listing of case studies and peer-reviewed publications utilizing PTMScan proteomic technology developed by Cell Signaling Technology.
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
Lymphoid lineage cells can be characterized using antibodies for cell type-specific markers, allowing cells to be visualized using flow cytometry or IHC.
Products and Related Resources for Adaptive Immune Response SARS-CoV-2 Research
A scientific resource for the F-Box protein domain containing information on structure, function, and domain binding to ubiquitin in protein degradation pathways.
Catalog numbers in tabular format for control cell extracts and proteins with links to product pages.
Interact with this CAR-T signaling pathway to learn how the combination of extracellular and intracellular domains, including CD8, CD28, 4-1BB, OX40, or CD27, exert antitumor effects.
Products and Related Resources for Virus Detection and Innate Immune Activation SARS-CoV-2 Research