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Abnormal cell-cell communication, for example disrupted presynaptic input, as well as disrupted intracellular signaling contribute to the pathogenesis of neurodegenerative disease.
A scientific resource for the BROMO protein domain containing information on structure, function, and binding to acetylated-lysine residues during chromatin remodeling.
Discover the insulin signaling pathway and its role in glucose metabolism & diabetes. Learn more about insulin action here.
Catalog numbers in tabular format for control cell extracts and proteins with links to product pages.
Streamline your neurodegeneration therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Interactive p38 MAPK pathway. Learn how p38 MAPK is involved in regulation of HSP27, MAPKAPK-2, MAPKAPK-3, & several transcription factors.
Expert-reviewed interactive pathway providing a current overview of Inhibition of Apoptosis Signaling.
Expert-reviewed interactive neuroscience pathways providing current overviews of Parkinson's and Alzheimer's Disease signaling, as well as links to products from CST.
Validation for flow cytometry antibodies from CST Cell Signaling Technology
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
Expert-reviewed interactive pathway providing a current overview of the Inflammasome Signaling Pathway.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
SimpleChIP Kits and Antibodies validated in-house by our antibody development scientists correlated to positive and negative control primers.
Use our protocol compatibility table to understand which immune signaling and phenotyping antibodies will work together in your multicolor flow cytometry experiment.
Expert-reviewed interactive dopamine signaling pathway providing a current overview of Dopamine in Parkinson's Disease. Learn more here.
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
The Cre Recombinase (D7L7L) XP Rabbit mAb #15036 has a "recombinant" sensitivity. Therefore, it can detect Cre in transgenic mouse models. In contrast, the Cre Recombinase (D3U7F) Rabbit mAb #12830 has a "transfected only" sensitivity because it has been validated using only transfected Cre recombinase; it does not detect Cre in transgenic mouse models.
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
CST’s Small Grants Program supports regional non-profit organizations that enrich our communities and protect our ecosystems. Twice a year, grant proposals are reviewed by our three employee-lead committees that focus on community grants, education in science, and environmental conservation.
Concerns About Shellfish Growth Causes Local Nonprofits and Private Industry to Team Up to Test Rivers for CO2 Levels