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Interact with this signaling pathway showing immune checkpoint regulation in the tumor microenvironment, including targets such as PD-L1, GITR, TIM-3, CTLA-4, OX40, and more.
Expert-reviewed interactive pathway providing a current overview of T Cell Receptor (TCR) Signaling.
This interactive guide shows the most important cell and functional state markers for tumor-infiltrating immune cells in mice.
Expert-reviewed diagram providing a current overview of the m6A RNA pathway with references to its role in tumor development
Learn about BCR signaling and how it can lead to changes in cell metabolism, gene expression, and cytoskeletal organization. Click here.
There are a number of markers that can be used to distinguish the many cell types of the central and peripheral nervous system during development, adult neurogenesis, and the pathogenesis of neurodegenerative disorders.
This interactive guide shows the key cell and functional state markers for tumor-infiltrating immune cells in humans.Web Location: Immunology and Inflammation
Interact with this CAR-T signaling pathway to learn how the combination of extracellular and intracellular domains, including CD8, CD28, 4-1BB, OX40, or CD27, exert antitumor effects.
Expert-reviewed interactive pathway providing a current overview of Contribution of Extracellular Matrix to EMT Signaling.
Expert-reviewed interactive pathway providing a current overview of Death Receptor Signaling.
Expert-reviewed interactive pathway providing a current overview of PTM Crosstalk Signaling.
Expert-reviewed interactive diagram of Rheumatoid Arthritis Pathogenesis and relevant antibodies for studying targets associated with the autoimmune disease.
Explore the NFkB pathway and its impact on inflammation and immune responses. Click here to learn more about this signaling pathway.
Study the PKC pathway's role in cellular signaling and regulation. Explore the molecular mechanisms & signaling events governed by this pathway. Click.
Expert-reviewed interactive diagrams providing current overviews of neuronal and glial cell markers, as well as links to products from CST.
The ESC and Lineage Markers diagram provides an overview of ESC differentiation along lineage-specific pathways and links to products from CST.
Expert-reviewed interactive pathway providing a current overview of Regulation of Microtubule Dynamics.
Expert-reviewed interactive pathway providing a current overview of TLR signaling.
Unravel the HER2 signaling pathway and its role in cell growth and cancer. Explore the molecular mechanisms and signaling events. Click here.
Expert-reviewed interactive pathway providing a current overview of Regulation of eIF4E and p70 S6K.
Discover the PI3K Akt pathway and its crucial role in cell growth and survival. Click here to learn more & gain insights into this important signaling cascade
Expert-reviewed interactive pathway providing a current overview of the Warburg Effect.
A number of growth factors and cytokines can induce an Epithelial-Mesenchymal Transition (EMT) in tumor cells.
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
Learn how RNA-binding proteins influence RNA regulation and epitranscriptomics and contribute to the progression of a variety of diseases.
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
Overview of Adhesion and Extracellular Matrix signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources.
