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Discover the top epigenetic markers that you should look out for in prostate cancer research.
ChIP-seq is a powerful technique that combines ChIP and next-generation sequencing (NGS) to study DNA-protein interactions across the entire genome, but it is only as good as the quality of the antibody used in the ChIP experiment.
Explore the AMPK pathway and its role in cellular energy homeostasis. Uncover the mechanisms of energy regulation. Learn more here.
Discover the phosphoinositide pathway's role in cellular signaling and membrane dynamics. Click here to read more about PI signaling here.
List of publications based on primary research done by the Cancer Research Group at CST (2002-2013).
Expert-reviewed interactive pathway providing a current overview of ATP-Dependent Chromatin Remodeling Complexes.
The Histone Modification Table provides a referenced list of many known histone modifications, associated modifying enzymes, and proposed functions.
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
This interactive guide shows the most important cell and functional state markers for tumor-infiltrating immune cells in mice.
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
A kinome diagram showing the TKL group of protein kinases from Cell Signaling Technology.
A kinome diagram showing the CK1 family of protein kinases from Cell Signaling Technology.
Kinome diagram showing the STE group of protein kinases from Cell Signaling Technology.
Kinome diagram showing protein kinases that are not assigned to any other category.
A kinome diagram showing the CMGC group of protein kinases from Cell Signaling Technology.
A kinome diagram showing the ACG group of protein kinases from Cell Signaling Technology.
This video demonstrates the technique used for splitting adherent cell lines with trypsinization.
Learn about the history of Cell Signaling Technology and our commitment to providing reproducible tools to move your science forward.
Understanding the underlying biology of fibrosis is critical for the diagnosis, treatment, and management of cardiac fibrosis, nonalcoholic steatohepatitis (NASH), and other fibrotic diseases
Why are antigen retrieval and antibody diluent important for the immunohistochemistry protocol? Our IHC expert offers protocol advice.
The comprehensive CST catalog of rigorously tested and validated products related to cell cycle regulation, DNA damage, and cell death and viability.
This video demonstrates the technique used for splitting suspension cell lines.
An overview of oh mass spectrometry-based proteomics studies can be a powerful tool for drug discovery and development
Profile protein abundance in cells and tissues using multiplexed sample labeling with Tandem Mass Tags and LC-MS/MS.
A scientific resource for the HECT protein domain containing information on structure, function, and domain binding in ubiquitin-mediated protein degradation.