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Explore the NFkB pathway and its impact on inflammation and immune responses. Click here to learn more about this signaling pathway.
Discover the insulin signaling pathway and its role in glucose metabolism & diabetes. Learn more about insulin action here.
Expert-reviewed interactive pathway providing a current overview of TLR signaling.
Necrosis has been classically defined as an unprogrammed form of cell death that occurs in response to overwhelming chemical or physical insult.
Expert-reviewed interactive pathway providing a current overview of Inhibition of Apoptosis Signaling.
Expert-reviewed interactive pathway providing a current overview of Death Receptor Signaling.
Products and Related Resources for Virus Detection and Innate Immune Activation SARS-CoV-2 Research
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.
Products and Related Resources for Cytokines and Inflammation SARS-CoV-2 Research
Understanding how TLR signaling is activated by molecular patterns is relevant not only to their role in combating infection but also in cancer.
Expert-reviewed interactive pathway providing a current overview of the Inflammasome Signaling Pathway.
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
Western Blotting troubleshooting guide for easy to solve high and low background issues.
Information and case study data for the PTMScan Direct Apoptosis/Autophagy Service offered by CST.
Discover the PI3K Akt pathway and its crucial role in cell growth and survival. Click here to learn more & gain insights into this important signaling cascade
Information and case study data for the PTMScan Direct Ser/Thr Kinases Service, which allows for the targeted screening of a defined set of protein modification sites.
Several different assays can be used by scientists to measure metabolism in a variety of contexts. These include methods to determine metabolic rates, key signaling pathways, and environmental cues.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Expert-reviewed interactive pathway providing a current overview of T Cell Receptor (TCR) Signaling.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
Recent advancements including next-generation proteasome inhibitors, monoclonal bispecific antibodies, antibody-drug conjugates, and CAR-T therapies that have changed the therapeutic landscape for multiple myeloma.
Learn here about the HIF-1 signaling pathway and its impact on oxygen homeostasis and cellular adaptation. Click here.
Learn about BCR signaling and how it can lead to changes in cell metabolism, gene expression, and cytoskeletal organization. Click here.
Study the intricate machinery of the apoptosis signaling pathway. Click here to learn more and gain insights into programmed cell death mechanisms.
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
The Histone Modification Table provides a referenced list of many known histone modifications, associated modifying enzymes, and proposed functions.
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.