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It is possible to see a doublet with our Phospho-c-Jun (Ser73) (D47G9) XP Rabbit mAb #3270 in some extracts. This is because #3230 can recognize JunD phosphorylated at Ser100. Phospho-c-Jun (Ser73) is the higher band at approximately 48 kDa, whereas phospho-JunD (Ser100) is the lower band at approximately 42 kDa.
Information and case study data for the PTMScan Direct Apoptosis/Autophagy Service offered by CST.
Cell Signaling Technology events including conference, vendor show and event listings.
A demonstration of the perils of deviating from Cell Signaling Technology's recommended protocols.
Hallmarks of Antibody Validation: Ranged Strategy. Binary models are not always readily available and can be time-consuming to produce for validating an antibody.
A ranged validation strategy includes both endogenous and heterologous models that express high, moderate, and low levels of the target of interest.
A Hallmark of Cancer, sustaining proliferative signaling is used by cancer cells to stimulate growth and relies on Akt, MAPK/Erk, and MTOR pathways.
As a new antibody is developed, Cell Signaling Technology scientists test the antibody’s stability and activity
A scientific resource for the coiled coil (CC) protein domain containing information on structure, function, and domain binding.
Maximize your research with our CUT&RUN Kit. Streamline chromatin profiling with our efficient, user-friendly tools designed for deeper, more insightful analyses.
The regulation of ER stress and autophagy during viral infection is an important factor in the balance of virus and host survival.
Autophagy is more than just the bulk degradation of intracellular components. It can also selectively degrade specific organelles, pathogens, and proteins.
Regulation of cell death due to viral infection is important for host survival. In this series, we look at pathways regulated through cellular responses to viruses.
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
This post explores common T cell types, their roles in modulating immune cell response, and T cell activation via interaction with cell surface receptors.
Lymphoma is a cancer of the lymphatic system, a key part of the body’s immune system. Treatment options & patient prognoses differ based on lymphoma type.
Summary of human oncogenes and tumor suppressor genes sorted by signaling pathway.
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
A recent publication highlights the advantages and disadvantages of different approaches to multiplex IHC/IF and explains how these methods differ.
Non-neuronal cells like microglia and astrocytes play critical roles in maintaining proper neuronal function, development, and disease.
Expert-reviewed interactive diagrams providing current overviews of neuronal and glial cell markers, as well as links to products from CST.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
SimpleChIP Kits and Antibodies validated in-house by our antibody development scientists correlated to positive and negative control primers.
Checkpoint inhibitors, targeted antibodies, adoptive cell therapy, and cancer vaccines are promising immunotherapies with recent therapeutic developments.
World Cancer Day raises awareness for cancer prevention, detection, and treatment. Learn about the scientific breakthroughs that are closing the care gap.
Stress granules are a cellular defense mechanism against stress but disruption in disassembly can lead to toxic proteins and neurodegenerative diseases.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
A chronological listing of case studies and peer-reviewed publications utilizing PTMScan proteomic technology developed by Cell Signaling Technology.
Expert-reviewed interactive pathway providing a current overview of T Cell Receptor (TCR) Signaling.
June 2008, CST funded $90,000 for Beverly High School to promote science education.
