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Expert-reviewed diagram providing a current overview of the m6A RNA pathway with references to its role in tumor development
Guest blogger Dr Gregory discusses research to define the epitranscriptome, including modifications that increase tRNA stability and prevent degradation.
Learn how RNA-binding proteins influence RNA regulation and epitranscriptomics and contribute to the progression of a variety of diseases.
Streamline your neurodegeneration therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
There is still much to learn about the hidden layer of gene regulation—the chemical modification of RNA. What is the effect of m6A, the most abundant mRNA modification observed in eukaryotes?
Hallmarks of Antibody Validation-Complementary Strategies that Employ Western Blot, Immunohistochemistry (IHC), Immunofluorescence (IF/ICC), Flow Cytometry, Histone Antibody, ChIP-qPCR, ChIP-seq.
Complementary strategies provide vital information regarding antibody specificity or functionality and can be tailored to the nature of the downstream assay.