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A scientific resource for the PX protein domain containing information on structure, function, and domain binding to phospholipids.
Several different assays can be used by scientists to measure metabolism in a variety of contexts. These include methods to determine metabolic rates, key signaling pathways, and environmental cues.
Stress granules are a cellular defense mechanism against stress but disruption in disassembly can lead to toxic proteins and neurodegenerative diseases.
A scientific resource for the POLO-Box protein domain containing information on structure, function, and domain binding to phospho-Ser/Thr motifs.
To help you pick the best reagents for your assay, this post reviews how companion reagents affect IHC results.
To help you pick the best reagents for your assay we will spend the next several posts reviewing how companion reagents affect IHC.
The key to identifying neurons, microglia, oligodendrocytes, and astrocytes lies in using antibodies that target protein biomarkers specifically expressed and localized within these cells.
Companion reagents influence the binding of a primary antibody to its epitope dramatically affecting results. Learn IHC troubleshooting tips in this series
Immunohistochemical Analysis. Learn the best ways to interpret IHC staining and understand experimental results accurately. Click here.
Information and case study data for the PTMScan Direct Ser/Thr Kinases Service, which allows for the targeted screening of a defined set of protein modification sites.
Learn how to visualize protein expression in tissue with immunohistochemistry (IHC). See examples of successfully optimized IHC assays.
Expert-reviewed interactive pathway providing a current overview of Cell Cycle G2/M DNA Damage Signaling.
The Kinase Library can determine the kinases likely to phosphorylate any given motif. Learn about the research enabling this phosphoproteomics revolution.
A journal club article elucidating the mechanisms of beta cell failure leading to type 2 diabetes.
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
Study the intricate cell cycle pathway's regulation of cell division and proliferation. Learn more here.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Streamline your neurodegeneration therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
List of publications based on primary research done by the Cancer Research Group at CST (2002-2013).
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.