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Resources results for "PSD-93"

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  • Resources (96)

PDZ Protein Domain

A scientific resource for the PDZ protein domain containing information on structure, function, and domain binding.

Post-Synaptic Signaling

Product Citations for CST's Erk Antibodies

Publications featuring Erk antibodies from Cell Signaling Technology.

PWWP Protein Domain

A scientific resource for the PWWP protein domain containing information on structure, function, and domain binding.

Resources

The 48 kDa band represents VASP phosphorylated at Ser239 and the 50 kDa band represents VASP phosphorylated at both Ser239 and Ser157. The hyper-phosphorylation that occurs when both serines are phosphorylated leads to a shift in the molecular weight. If you would like more information, please refer to Aizawa et al. (2003) Circ Res 93, 406-13 (PMID: 12919948; https://www.ncbi.nlm.nih.gov/pubmed/12919948).

mTOR Signaling

Discover the mTOR pathway and its role in cellular growth and metabolism. Click here to explore the intricacies of this vital signaling pathway.

Phosphoinositide (Lipid) Signaling

Discover the phosphoinositide pathway's role in cellular signaling and membrane dynamics. Click here to read more about PI signaling here.

Toll-like Receptor Signaling

Expert-reviewed interactive pathway providing a current overview of TLR signaling.

Resources

It is possible to see three bands for the large subunit of cleaved caspase-3. The bands all represent cleavage at Asp175. However, the distinction between the three is the extent of processing at the amino termini of the proteins [see Fernandes-Alnemri, T. et al. (1996) Proc Natl Acad Sci U S A. 93(15), 7464-9 (PMID: 8755496; http://www.ncbi.nlm.nih.gov/pubmed/8755496)]. Processing of caspase-3 into its fully active form is a two-step process. Step 1 involves cleavage at Asp175, which generates the 20 kDa large subunit and the 12 kDa small subunit. In step 2, the 20 kDa large subunit is further cleaved at Asp9, probably through auto-catalytic activity. The removal of the first nine amino acids of the pro-domain results in the 19 kDa subunit. Further cleavage can also occur more slowly at Asp28 to generate the fully mature 17 kDa subunit. Therefore, any accumulation of the 20 and 19 kDa subunits is presumabl…

Angiogenesis

Expert-reviewed interactive pathway providing a current overview of angiogenesis pathways and links to products by Cell Signaling Technology.

Immunology/Inflammation

Explore the complex inflammation signaling pathways. Click here to learn more and understand the molecular basis of inflammation.

Translational Control

Expert-reviewed interactive pathway providing a current overview of Translational Control.

Cell Cycle Regulation

Study the intricate cell cycle pathway's regulation of cell division and proliferation. Learn more here.

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Kinase Signaling

Expert-reviewed interactive pathway providing a current overview of ErbB/HER Signaling.

Human Immune Cell Marker Guide

This interactive guide shows the key cell and functional state markers for tumor-infiltrating immune cells in humans.Web Location: Immunology and Inflammation

RNA Regulation, Translational Control, and Protein Synthesis

Resources for the study of Translational Control, Protein Synthesis, and RNA Regulation including antibodies and associated reagents and interactive pathway diagrams.

G1/S Checkpoint

Expert-reviewed interactive pathway providing a current overview of Cell Cycle G1/S Checkpoint Signaling.

Frequently Asked Questions

Frequently asked questions using our products while doing your research

Learn & Support

Get information on ordering or contacting Cell Signaling Technology. CST is happy to answer your questions. Select the team you need to contact.

How Do I Measure Metabolism?

Several different assays can be used by scientists to measure metabolism in a variety of contexts. These include methods to determine metabolic rates, key signaling pathways, and environmental cues.

Still in the Dark: AMD Patients Wait for Answers

Our summary of recent findings published in Nature, which indicate that non-performing antibodies were used in many recent macular degeneration studies.

Jak and Cytokine Receptor Mutants in Cancer Table

Jak and cytokine receptor mutations found in various cancers, along with the corresponding PubMed reference(s).

Western Blot Normalization: Am I setting up my loading controls correctly?

Loading control proteins are often more abundant than the protein of interest, which can lead to the signal exceeding the linear dynamic range of detection

Ubiquitin Ligase Table

The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).

Histone Modification Table

The Histone Modification Table provides a referenced list of many known histone modifications, associated modifying enzymes, and proposed functions.

Publications By Our Scientists

A comprehensive list of peer-reviewed publications from Cell Signaling Technology.

Cancer Publications from CST

List of publications based on primary research done by the Cancer Research Group at CST (2002-2013).

PTMScan® Proteomic Services: Case Study and Publications

A chronological listing of case studies and peer-reviewed publications utilizing PTMScan proteomic technology developed by Cell Signaling Technology.

PTMScan® Motif Antibody Kits

PTMScan Motif Antibody Kits from Cell Signaling Technology