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Information and case study data for the PTMScan Direct Tyrosine Kinases Service from Cell Signaling Technology.
A list of important CD markers that includes links to PhosphoSitePlus, Uniprot, and products from Cell Signaling Technology.
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.
Listing of IHC-related scientific posters and papers involving scientists from Cell Signaling Technology.
Explore the mitochondrial apoptosis pathway and its role in programmed cell death. Read more about this essential pathway here.
Expert-reviewed interactive pathway providing a current overview of Inhibition of Apoptosis Signaling.
Autophagy helps normal cells maintain homeostasis and acts as a survival mechanism in response to stress, where ULK1 plays an important role in signaling.
Hypoxia causes cellular stress and alters normal metabolic activity. These pathways allow cells to survive and recover during bouts of low oxygen.
Autophagy is more than just the bulk degradation of intracellular components. It can also selectively degrade specific organelles, pathogens, and proteins.
Abnormal cell-cell communication, for example disrupted presynaptic input, as well as disrupted intracellular signaling contribute to the pathogenesis of neurodegenerative disease.
iPRM is a multiplexed LC/MS assay service that combines the specificity of mass spectrometry, the throughput of an immunoassay, and the power of multiplexing to accelerate the time-to-market of your drug and/or diagnostic test.
Jan 2012, Ventana to collaborate with Pfizer & CST on companion diagnostic to identify lung cancer patients with ALK gene rearrangements.
A recent publication highlights the advantages and disadvantages of different approaches to multiplex IHC/IF and explains how these methods differ.
Metabolism defines all of the chemical changes or processes within cells, tissues, and organisms that sustain cellular homeostasis.
Immunohistochemistry Protocol (Paraffin): easy to follow directions describing the step by step experimental procedure.
Expert-reviewed interactive dopamine signaling pathway providing a current overview of Dopamine in Parkinson's Disease. Learn more here.
Selecting antibodies and a protocol for flow cytometry comes with several considerations which are discussed in this webinar.
Designing or troubleshooting flow cytometry experiments to analyze intracellular signaling? Here’s what you need to know.
If you’re only looking at surface markers in your flow cytometry, you’re missing out! We’ll discuss several protocol approaches to multiplexing so that you can analyze both surface markers and intracellular targets.
Cell Signaling Technology (CST), a leading provider of antibodies, kits, and services, was honored with the 2017 CiteAb Award for &quoPTM Antibody Company of the Year" and for a third year in a row with the award for "Researchers’ Choice."
Cell Signaling Technology (CST), a leading provider of antibodies, kits, and services, was honored with the 2017 CiteAb Award for “PTM Antibody Company of the Year” and for a third year in a row with the award for “Researchers’ Choice.”
Use these quick reference tables to determine compatible fluorophore combinations for flow cytometry experiments using parallel or co-linear excitation.
Identification of ALK and ROS1 fusion proteins in non-small cell lung cancer (NSCLC) at Cell Signaling Technology.
Will an antibody validated for WB perform as expected in an IF experiment? Here, we compare an IF-validated mAb from CST to one from another vendor.
What makes an antibody monoclonal, polyclonal, or recombinant? Is one better than the other, or are they all designed for different purposes?
Distinguish living cells from dead or dying cells with viability dyes.
CiteAb Names Cell Signaling Technology, "Antibody Company of the Year" and "Researchers’ Choice"