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Information and case study data for the PTMScan Direct Apoptosis/Autophagy Service offered by CST.
Information and case study data for the PTMScan Direct PI3K/Akt Service offered by CST, which allows for targeted screening of 105 proteins within the Akt pathway.
Information and case study data for the PTMScan Direct Ser/Thr Kinases Service, which allows for the targeted screening of a defined set of protein modification sites.
Compare Cell Signaling Technology's Akt antibodies against one another to determine optimal applications
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
Our Akt Antibody #9272 detects all 3 isoforms of Akt: Ak1, Akt2, and Akt3.
The Phospho-Akt (Thr308) Antibody #9275 will recognize all 3 isoforms of Akt: Ak1, Akt2, and Akt3.
Overview of PI3K/Akt signaling pathways, antibodies and related reagents, interactive pathway diagrams, and other technical resources.
Phospho-Akt product and resources including product citations, educational videos and pathways, product selection tools and comparison data from Cell Signaling Technology
Discover the PI3K Akt pathway and its crucial role in cell growth and survival. Click here to learn more & gain insights into this important signaling cascade
A Hallmark of Cancer, sustaining proliferative signaling is used by cancer cells to stimulate growth and relies on Akt, MAPK/Erk, and MTOR pathways.
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
The Akt Binding Partners Table provides a list of proteins that bind to Akt along with their effects, activities, and corresponding PubMed reference(s).
Discover the mTOR pathway and its role in cellular growth and metabolism. Click here to explore the intricacies of this vital signaling pathway.
Expert-reviewed interactive pathway providing a current overview of Cell Cycle G1/S Checkpoint Signaling.
Listing of reference table resources for cellular regulation and signaling research
"PI3K/Akt signaling is close to my heart because certain diseases that have cropped up in my family are linked to specific proteins in this pathway."
Zika virus turns off Akt signaling to hijack autophagy in developing neural tissue
Video Tutorial on PI3K / Akt Signaling created by CST on upstream stimuli and downstream effects on cellular events (autophagy, mTOR)
Study the PKC pathway's role in cellular signaling and regulation. Explore the molecular mechanisms & signaling events governed by this pathway. Click.
Publications featuring Akt antibodies from Cell Signaling Technology.
Synopsis of CST scientists' publication in the journal Science Signaling describing phosphorylation patterns associated with non-small cell lung cancer (NSCLC).
Video tutorials illustrate the science behind cellular processes and signaling pathways.
Find Pathways and Diagrams By Disease Area
Expert-reviewed interactive pathway providing a current overview of Inhibition of Apoptosis Signaling.
Learn more about stem cell pathways and the transcription factors Oct-4, Sox2, and Nanog are essential for maintaining the pluripotent state of stem cells.
Discover the insulin signaling pathway and its role in glucose metabolism & diabetes. Learn more about insulin action here.
Study the IL-6 pathway and its impact on inflammation and immune regulation. Delve into the intricacies of this signaling cascade. Click here.
The three main purposes of metabolism are the conversion of food to energy; the conversion of nutrients to proteins, carbohydrates, lipids, and nucleic acids; and the elimination of nitrogenous wastes. There is a strong correlation between metabolic chan