Basket Updated
0
Items added
Information and case study data for the PTMScan Direct Cell Cycle and DNA Damage Service offered by CST.
Tau is a microtubule-associated protein found in neurons, and its function is to stabilize axonal microtubules. Hyperphosphorylated tau is a hallmark of several neurodegenerative diseases including Alzheimer’s disease.
Information and case study data for the PTMScan Direct Ser/Thr Kinases Service, which allows for the targeted screening of a defined set of protein modification sites.
While the Tau protein is phosphorylated in normal, healthy brain, it becomes hyperphosphorylated in neurodegenerative diseases, like Alzheimer's.
Expert-reviewed interactive pathway providing a current overview of Cell Cycle G1/S Checkpoint Signaling.
Interested in studying senescence? Understanding cell cycle arrest is critical to many fields of research, including development, aging, and cancer.
iPRM is a multiplexed LC/MS assay service that combines the specificity of mass spectrometry, the throughput of an immunoassay, and the power of multiplexing to accelerate the time-to-market of your drug and/or diagnostic test.
Illustration of Motif Antibody Coverage
A scientific resource for the BROMO protein domain containing information on structure, function, and binding to acetylated-lysine residues during chromatin remodeling.
Expert-reviewed interactive pathway providing a current overview of the molecular and cellular biology of Alzheimer’s Disease.
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
Learn more about commonly used chemical modulators to study cellular physiology and biology.
Overview of GPCR, Calcium, cAMP Signaling Resources, interactive pathway diagrams, and other technical resources.
Expert-reviewed interactive pathway providing a current overview of Nuclear Receptor Signaling.
Summary of human oncogenes and tumor suppressor genes sorted by signaling pathway.
Cellular senescence is characterized by irreversible cell-cycle arrest in combination with a distinct secretory phenotype and expanded lysosomes in response to stress. Senescent cells accumulate in tissues during aging, and various markers of senescence
Expert-reviewed interactive dopamine signaling pathway providing a current overview of Dopamine in Parkinson's Disease. Learn more here.
The nuclear receptor signaling plays important roles in cell differentiation, proliferation, metabolism, and other physiological processes. Click here.
Discover the PI3K Akt pathway and its crucial role in cell growth and survival. Click here to learn more & gain insights into this important signaling cascade
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Learn about the differences between BRCA1 and BRACA2 gene mutations and the search for new therapies targeting DNA repair pathways beyond PARP inhibitors.
Cellular senescence is defined by permanent cell cycle arrest. Senescent cells accumulate with age and contribute to normal aging and age-related disorders
A comprehensive list of peer-reviewed publications from Cell Signaling Technology.
Find validated CST® matched antibody pairs and streamline the development of your High-Throughput ELISA-Like Immunoassays for screening.
List of publications based on primary research done by the Cancer Research Group at CST (2002-2013).
The Ubiquitin Ligase Table provides a comprehensive list of E3 ubiquitin ligases along with their substrates and corresponding PubMed reference(s).
p16 is an important cervical cancer biomarker but studies have shown variable expression levels, suggesting an IHC-validated p16 INK4A antibody is needed.
Explore the intricate Wnt Beta Catenin pathway & its role in cell development and disease. Learn more about the signaling cascade of this crucial pathway.
"PI3K/Akt signaling is close to my heart because certain diseases that have cropped up in my family are linked to specific proteins in this pathway."
