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Explore the NFkB pathway and its impact on inflammation and immune responses. Click here to learn more about this signaling pathway.
Products and Related Resources for Virus Detection and Innate Immune Activation SARS-CoV-2 Research
Learn how CUT&RUN can be performed in as little as 1-2 days using low cell number samples, and how CUT&RUN has been employed to study epigenetic remodeling and alternative splicing directed by the NF-κB pathway downstream of a viral oncoprotein.
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
Expert-reviewed interactive pathway providing a current overview of Death Receptor Signaling.
SimpleChIP Kits and Antibodies validated in-house by our antibody development scientists correlated to positive and negative control primers.
Expert-reviewed signaling pathway providing a current overview of adherens junction dynamics and links to products by Cell Signaling Technology.
Expert-reviewed diagram providing a current overview of the Senescence Signaling pathway with references to its role in cell cycle
Expert-reviewed interactive pathway providing a current overview of the Warburg Effect.
Expert-reviewed interactive pathway providing a current overview of angiogenesis pathways and links to products by Cell Signaling Technology.
Discover the epigenetic drivers that help drive MDS / AML cancers
Case Study 4: Exceptional Performance of XP Monoclonal Antibodies from Cell Signaling Technology.
Learn how RNA-binding proteins influence RNA regulation and epitranscriptomics and contribute to the progression of a variety of diseases.
A number of growth factors and cytokines can induce an Epithelial-Mesenchymal Transition (EMT) in tumor cells.
Overview of Adhesion and Extracellular Matrix signaling networks, antibodies and related reagents, interactive pathway diagrams, and technical resources.
The accuracy of western blot results relies heavily on the quality of the primary antibody used. CST™ antibodies are validated using multiple experiments.
A Hallmark of Cancer, sustaining proliferative signaling is used by cancer cells to stimulate growth and relies on Akt, MAPK/Erk, and MTOR pathways.
Mass spectrometry-based proteomic methods like PTMScan can be applied in translational research. For example to identify novel biomarkers of disease
Chromatin Immunoprecipitation Workflow Solutions for ChIP-qPCR and ChIP-seq
Protein-DNA interactions mediate epigenetic processes. Researchers studying these interactions need a means of analyzing when & where they occur on the genome.
Listing of IHC-related scientific posters and papers involving scientists from Cell Signaling Technology.
A chronological listing of case studies and peer-reviewed publications utilizing PTMScan proteomic technology developed by Cell Signaling Technology.
Overview of epigenetic and chromatin regulation pathways, antibodies and related reagents, interactive pathway diagrams, and technical resources for epigenetics research.
Interested in studying senescence? Understanding cell cycle arrest is critical to many fields of research, including development, aging, and cancer.
The ELISA method has many variations, all of which rely on complex of an antigen and an antibody/enzyme conjugate. Signal is generated by turnover of substrate.
List of publications based on primary research done by the Cancer Research Group at CST (2002-2013).
Learn here about the HIF-1 signaling pathway and its impact on oxygen homeostasis and cellular adaptation. Click here.
Stress granules are a cellular defense mechanism against stress but disruption in disassembly can lead to toxic proteins and neurodegenerative diseases.
Expert-reviewed interactive pathway providing a current overview of T Cell Receptor (TCR) Signaling.
We offer 3 MitoTracker® products, MitoTracker® Green FM #9074, MitoTracker® Deep Red FM #8778 and MitoTracker® Red CMXRos #9082. MitoTracker® Deep Red FM #8778 and MitoTracker® Red CMXRos #9082 are well retained after methanol fixation as outlined in our Product Usage Information. MitoTracker® Green FM #9074, on the other hand, is only useful for live cell imaging as the dye is not well retained after fixation with aldehydes or alcohols.