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Expert-reviewed interactive pathway providing a current overview of Regulation of eIF4E and p70 S6K.
Resources for the study of Translational Control, Protein Synthesis, and RNA Regulation including antibodies and associated reagents and interactive pathway diagrams.
Products and Related Resources for Viral Entry, Replication, and Transcription SARS-CoV-2 Research
Expert-reviewed interactive pathway providing a current overview of Translational Control.
Cell Signaling Technology pathways by research area
Expert-reviewed interactive pathway providing a current overview of ErbB/HER Signaling.
Learn about the antibodies, custom reagents, and ready-to-use cell assay kits to support your CAR-T therapy development.
Listing of IHC-related scientific posters and papers involving scientists from Cell Signaling Technology.
Anti-CAR linker antibodies confirm CAR surface expression for CAR-T therapy, regardless of antigen specificity; 2023 winner of the CiteAb Innovation Award.
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
Immunoprecipitation Protocol (For Native Protein): easy to follow directions describing the step by step experimental procedure.
Guest blogger Dr Gregory discusses research to define the epitranscriptome, including modifications that increase tRNA stability and prevent degradation.
Expert-reviewed interactive pathway providing a current overview of Cell Cycle G1/S Checkpoint Signaling.
Identify microglia by using these antibodies, which are designed to detect protein biomarkers specifically expressed within these cells.
Apoptosis is a type of programmed cell death that occurs normally throughout the lifespan and can also occur in response to harmful stimuli. Apoptotic cells are identified by their altered morphology, caspase activation, and the presence of damaged DNA.
The ESC and Lineage Markers diagram provides an overview of ESC differentiation along lineage-specific pathways and links to products from CST.
A multiple-antibody strategy is a powerful approach to antibody validation. The most common method to achieve this is to immunoprecipitate (IP) the target with one antibody and subsequently detect it by western blotting with another antibody against the
Expert-reviewed interactive pathway providing a current overview of Histone Methylation.
The key to identifying neurons, microglia, oligodendrocytes, and astrocytes lies in using antibodies that target protein biomarkers specifically expressed and localized within these cells.
SimpleChIP Kits and Antibodies validated in-house by our antibody development scientists correlated to positive and negative control primers.
Learn how RNA-binding proteins influence RNA regulation and epitranscriptomics and contribute to the progression of a variety of diseases.
In-Cell Western Protocol: easy to follow directions describing the step by step experimental procedure.
Immunofluorescence Protocol for Biotin-Conjugated Antibodies: easy to follow directions describing the step by step experimental procedure.
Learn here about the HIF-1 signaling pathway and its impact on oxygen homeostasis and cellular adaptation. Click here.
Stress granules are a cellular defense mechanism against stress but disruption in disassembly can lead to toxic proteins and neurodegenerative diseases.
Immunoprecipitation Protocol Utilizing Magnetic Separation (For Analysis By Western Blot): easy to follow directions describing the step by step experimental procedure.
Compare Cell Signaling Technology's Akt antibodies against one another to determine optimal applications
A number of growth factors and cytokines can induce an Epithelial-Mesenchymal Transition (EMT) in tumor cells.